Biomarkers by platforms
Bevital´s panels currently includes 145 biomarkers analysed by 9 different analytical platforms. Click on the biomarker for detailed informations and literature.
Platform A
Short-chain fatty acids.
GC-MS/MS
Vol.: 50 µL
Concentrations in µmol/L
Platform B
TCA metabolites and intermediates. Amino and carboxylic acids.
GC-MS/MS
Vol.: 50 µL
Concentrations in µmol/L
- 2-Aminoadipic acid
- 2-Hydroxybutyrate
- 3-Hydroxybutyrate
- 3-Hydroxyisobutyrate
- Acetoacetate
- Carboxyethyllysine
- Carboxymethyllysine
- Citrate
- Cystathionine
- Fumarate
- Glycine
- Histidine
- Isocitrate
- Kynurenines
- Lactate
- Malate
- Methionine
- Methylmalonic acid
- Ornithine
- Other amino acids: aspartic acid (Asp), glutamic acid (Glu), lysine (Lys), alanine acid (Ala), phenylalanine (Phe), isoleucine (Ile), leucine (Leu), proline (Pro), valine (Val), asparagine (Asn), glutamine (Gln), threonine (Thr), and tyrosine (Tyr).
- Phenylacetylglutamine
- Pyruvate
- Sarcosine
- Serine
- Total cysteine
- Total homocysteine
- Tryptophan
- α-Hydroxyglutaric acid
- α-Ketoglutarate
- β–Alanine
- β-Aminoisobutyrate
Platform C
Charged, methylated or sulfur amino acids.
LC-MS/MS
Vol.: 35 µL
Concentrations in µmol/L
- 1-Methylhistidine
- 3-Methylhistidine
- Arginine
- Asymmetric dimethylarginine
- Betaine
- Carnitine
- Carnitine, total
- Choline
- Citrulline
- Creatine
- Creatinine
- Dimethylglycine
- Histidine
- Homoarginine
- Methionine
- Methionine sulfoxide
- Symmetric dimethylarginine
- Total cysteine
- Total homocysteine
- Trimethylamine N-oxide
- Trimethyllysine
- Derived index: HCC
Platform D
Kynurenine pathway and B vitamins (B1, B2, B3, B6).
LC_MS/MS
Vol.: 60 µL
Concentrations in µmol/L or nmol/L
- 4-Pyridoxic acid
- Cotinine
- Cystathionine
- Flavin mononucleotide
- Imidazole propionate
- Kynurenines
- Microbiota-derived indoles
- N1-methylnicotinamide
- Neopterin
- Nicotinamide
- Nicotinic acid
- Pyridoxal
- Pyridoxal 5-phosphate
- Pyridoxine
- Riboflavin
- Thiamine
- Thiamine monophosphate
- Trans-3-hydroxycotinine
- Trigonelline
- Trimethylamine N-oxide
- Tryptophan
- Derived indexes:
HK:XA ratio
HKr
Kyn/Trp ratio (KTR)
PAr
Platform E
Folate species and catabolites.
LC-MS/MS
Vol.: 60 µL
Concentrations in nmol/L
Platform F
Folate (B9) and cobalamin (B12).
Microbiological assay
Vol.: 15-35 µL
Concentrations in nmol/L or pmol/L
Platform G
Protein biomarkers and proteoforms.
MALDI-TOF MS
Vol.: 30 µL
Concentrations in µg/ml or %
Platform H
Lipid-soluble vitamins.
LC-MS/MS
Vol.: 50-100 µL
Concentrations in µmol/L or nmol/L
Platform I
Short-, medium- and and long-chain acylcarnitines.
LC (HILIC)-MS/MS
Vol.: 60 µL
Concentrations in µmol/L
- BB Butyrobetaine
- C0 Carnitine
- C2 Acetylcarnitine
- C3 Propionylcarnitine
- C3-DC Malonylcarnitine
- C4 Butyrylcarnitine
- C4-OH Hydroxybutyrylcarnitine
- C4-DC Succinylcarnitine
- iC5 Isovalerylcarnitine
- C5-DC Glutarylcarnitine
- C5:1 Tiglylcarnitine
- C6 Hexanoylcarnitine
- C8 Octanoylcarnitine
- C10 Decanoylcarnitine
- C12 Dodecanoylcarnitine
- C14 Tetradecanoylcarnitine
- C14-OH Hydroxytetradecanoylcarnitine
- C16 Hexadecanoylcarnitine
- C16-OH Hydroxyhexadecanoylcarnitine
- C18 Octadecanoylcarnitine
- C18-OH Hydroxyoctadecanoylcarnitine
- C18:1 Octadecenoylcarnitine
- C18:2 Octadecadienylcarnitine
July 10, 2024