BEVITAL AS

WORKFLOW

BEVITAL has optimized its entire workflow—from project evaluation to sample handling and data analysis—over the past 20 years.

At BEVITAL, our team can assist you in selecting biomarkers and panels tailored to your study design, research questions, and budget. We’ll recommend the biomarkers that best align with your research objectives, ensuring high-quality, reliable data with minimal sample use—all at competitive pricing.

A pre-analysis evaluation typically includes:

  • Your research questions and design of the project
  • Appropriate biomarker and panel selection
  • Sample type and volume requirements
  • Anticipated timeline for analyses completion
  • Commercial or collaborative contract
  • Contact persons for your project

At BEVITAL, our team can assist you in selecting biomarkers and panels tailored to your study design, research questions, and budget. We’ll recommend the biomarkers that best align with your research objectives, ensuring high-quality, reliable data with minimal sample use—all at competitive pricing.

A pre-analysis evaluation typically includes:

  • Your research questions and design of the project
  • Appropriate biomarker and panel selection
  • Sample type and volume requirements
  • Anticipated timeline for analyses completion
  • Commercial or collaborative contract
  • Contact persons for your project
1. Evaluation

Evaluation of your project by email or video conference is highly recommended to deliver optimal data from your precious biobank samples.​

2. Transportation

Samples have to be shipped on dry ice by recommended courier and agreed time point to avoid loss or thawing of samples.

3. Arrival at BEVITAL

Samples are stored immediately at -80°C to guarantee highest pre-analytical biomarker stability.​

4. Sample aliquotation

Samples are split into aliquots for analyses on different analytical platforms.

5. Sample analysis

Samples are analyzed and remaining material is stored at -80°C. Customer has to decide, if remaining material has to be destroyed or returned.

6. Data processing

Mass spectra are processed by in-house developed QC software and results stored as FileMaker database.

7. Quality control

External quality controls from DEKS, DEQAS, KEQAS, ERNDIM and LABQUALITY included in each set of samples are checked to monitor platform performance and to avoid assay errors and failures.​

8. Data analysis and report

Detailed lab data report is generated giving an overview of the results, assay performance, and reasons behind missing data, if any.

Optional data analysis is offered from basic statistical analyses to more advanced approaches.

1. Evaluation

Evaluation of your project by email or video conference is highly recommended to deliver optimal data from your precious biobank samples.​

2. Transportation

Samples have to be shipped on dry ice by recommended courier and agreed time point to avoid loss or thawing of samples.

3. Arrival at BEVITAL

Samples are stored immediately at -80°C to guarantee highest pre-analytical biomarker stability.​

4. Sample aliquotation

Samples are split into aliquots for analyses on different analytical platforms.

5. Sample analysis

Samples are analyzed and remaining material is stored at -80°C. Customer has to decide, if remaining material has to be destroyed or returned.

6. Data processing

Mass spectra are processed by in-house developed QC software and results stored as FileMaker database.

7. Quality control

External quality controls from DEKS, DEQAS, KEQAS, ERNDIM and LABQUALITY included in each set of samples are checked to monitor platform performance and to avoid assay errors and failures.​

8. Data analysis and report

Detailed lab data report is generated giving an overview of the results, assay performance, and reasons behind missing data, if any.

Optional data analysis is offered from basic statistical analyses to more advanced approaches.

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562 entries « 1 of 29 »
1.

Bakker, Lieke; Ramakers, Inez H G B; van Greevenbroek, Marleen M J; Backes, Walter H; Jansen, Jacobus F A; Schram, Miranda T; van der Kallen, Carla J H; Schalkwijk, Casper G; Wesselius, Anke; Ulvik, Arve; Ueland, Per M; Verhey, Frans R J; Eussen, Simone J P M; Köhler, Sebastian

The kynurenine pathway and markers of neurodegeneration and cerebral small vessel disease: The Maastricht Study Journal Article

In: J Neurol Sci, vol. 474, pp. 123522, 2025, ISSN: 1878-5883.

Abstract | Links | BibTeX

2.

Holthuijsen, Daniëlle D B; van Roekel, Eline H; Bours, Martijn J L; Ueland, Per M; Breukink, Stéphanie O; Janssen-Heijnen, Maryska L G; Konsten, Joop L; Keulen, Eric T P; McCann, Adrian; Brezina, Stefanie; Gigic, Biljana; Kok, Dieuwertje E; Ulrich, Cornelia M; Weijenberg, Matty P; Eussen, Simone J P M

Modeling how iso-caloric macronutrient substitutions are longitudinally associated with plasma kynurenines in colorectal cancer survivors up to 12 months post-treatment Journal Article

In: J Nutr Biochem, vol. 141, pp. 109910, 2025, ISSN: 1873-4847.

Abstract | Links | BibTeX

3.

Belen, Sergen; Patt, Nadine; Kupjetz, Marie; Ueland, Per M; McCann, Adrian; Gonzenbach, Roman; Bansi, Jens; Zimmer, Philipp

Vitamin B status is related to disease severity and modulated by endurance exercise in individuals with multiple sclerosis: a secondary analysis of a randomized controlled trial Journal Article

In: Am J Clin Nutr, vol. 121, no. 6, pp. 1403–1414, 2025, ISSN: 1938-3207.

Abstract | Links | BibTeX

4.

Dahl, Tuva B; Aftab, Friha; Prebensen, Christian; Berdal, Jan-Erik; Ueland, Thor; Barratt-Due, Andreas; Riise, Anne Ma Dyrhol; Ueland, Per Magne; Hov, Johannes R; Trøseid, Marius; Aukrust, Pål; Gregersen, Ida; Myhre, Peder L; Omland, Torbjørn; Halvorsen, Bente

Imidazole propionate is increased in severe COVID-19 and correlates with cardiac involvement Miscellaneous

2025, ISSN: 1532-2742.

Links | BibTeX

5.

Banjara, Sarala; Berggreen, Ellen; Igland, Jannicke; Åstrøm, Anne-Kristine; Midttun, Øivind; Bunæs, Dagmar; Sulo, Gerhard

Plasma levels of immune system activation markers Neopterin and Kynurenine-to-Tryptophan Ratio, and oral health among community-dwelling adults in Norway: a population-based, cohort study Journal Article

In: Acta Odontol Scand, vol. 84, pp. 218–225, 2025, ISSN: 1502-3850.

Abstract | Links | BibTeX

6.

Holthuijsen, Daniëlle D B; Rijnhart, Judith J M; Bours, Martijn J L; van Roekel, Eline H; Ueland, Per M; Breukink, Stéphanie O; Janssen-Heijnen, Maryska L G; Konsten, Joop L; Keulen, Eric T P; McCann, Adrian; Brezina, Stefanie; Gigic, Biljana; Ulrich, Cornelia M; Weijenberg, Matty P; Eussen, Simone J P M

Longitudinal associations of dietary intake with fatigue in colorectal cancer survivors up to 1 year post-treatment, and the potential mediating role of the kynurenine pathway Journal Article

In: Brain Behav Immun, vol. 126, pp. 144–159, 2025, ISSN: 1090-2139.

Abstract | Links | BibTeX

7.

Joisten, Niklas; Reuter, Marcel; Rosenberger, Friederike; Venhorst, Andreas; Kupjetz, Marie; Walzik, David; Schenk, Alexander; McCann, Adrian; Ueland, Per Magne; Meyer, Tim; Zimmer, Philipp

Exercise training restores longevity-associated tryptophan metabolite 3-hydroxyanthranilic acid levels in middle-aged adults Journal Article

In: Acta Physiol (Oxf), vol. 241, no. 5, pp. e70041, 2025, ISSN: 1748-1716.

Abstract | Links | BibTeX

8.

Jørgensen, Silje F; Braadland, Peder R; Ueland, Thor; Fraz, Mai S A; Michelsen, Annika E; Holm, Kristian; Osnes, Liv T; Trøseid, Marius; Ueland, Per Magne; Fevang, Børre; Aukrust, Pål; Hov, Johannes R

Tryptophan-kynurenine metabolites associate with inflammation and immunologic phenotypes in common variable immunodeficiency Journal Article

In: J Allergy Clin Immunol, 2025, ISSN: 1097-6825.

Abstract | Links | BibTeX

9.

Grytten, Elise; Laupsa-Borge, Johnny; Cetin, Kaya; Bohov, Pavol; Nordrehaug, Jan Erik; Skorve, Jon; Berge, Rolf K; Strand, Elin; Bjørndal, Bodil; Nygård, Ottar K; Rostrup, Espen; Mellgren, Gunnar; Dankel, Simon N

Inflammatory markers after supplementation with marine n-3 or plant n-6 PUFAs: A randomized double-blind crossover study Journal Article

In: J Lipid Res, vol. 66, no. 4, pp. 100770, 2025, ISSN: 1539-7262.

Abstract | Links | BibTeX

10.

Trollebø, Marte A; Tangvik, Randi J; Skeie, Eli; Nygård, Ottar; Eagan, Tomas M L; McCann, Adrian; Dierkes, Jutta

Metabolic profiles and malnutrition in hospitalized adults: A metabolomic cohort study Journal Article

In: JPEN J Parenter Enteral Nutr, vol. 49, no. 3, pp. 365–372, 2025, ISSN: 1941-2444.

Abstract | Links | BibTeX

11.

Valim, Valéria; Oliveira, Fabíola R; Miyamoto, Samira T; Serrano, Érica V; Balarini, Gabriela M; Tanure, Leandro A; Ferreira, Gilda A; Zandonade, Eliana; Brun, Johan G; Jonsson, Malin; Maeland, Elisabeth; Ulvik, Arve; Ueland, Per Magne; Jonsson, Roland; Mydel, Piotr M

Kynurenines and neopterin are interferon-gamma-inducible biomarkers for Sjögren's disease Journal Article

In: Rheumatology (Oxford), 2025, ISSN: 1462-0332.

Abstract | Links | BibTeX

12.

Wilson, Edward N; Umans, Jacob; Swarovski, Michelle S; Minhas, Paras S; Mendiola, Justin H; Midttun, Øivind; Ulvik, Arve; Shahid-Besanti, Marian; Linortner, Patricia; Mhatre, Siddhita D; Wang, Qian; Channappa, Divya; Corso, Nicole K; Tian, Lu; Fredericks, Carolyn A; Kerchner, Geoffrey A; Plowey, Edward D; Cholerton, Brenna; Ueland, Per M; Zabetian, Cyrus P; Gray, Nora E; Quinn, Joseph F; Montine, Thomas J; Sha, Sharon J; Longo, Frank M; Wolk, David A; Chen-Plotkin, Alice; Henderson, Victor W; Wyss-Coray, Tony; Wagner, Anthony D; Mormino, Elizabeth C; Aghaeepour, Nima; Poston, Kathleen L; Andreasson, Katrin I

Parkinson's disease is characterized by vitamin B6-dependent inflammatory kynurenine pathway dysfunction Journal Article

In: NPJ Parkinsons Dis, vol. 11, no. 1, pp. 96, 2025, ISSN: 2373-8057.

Abstract | Links | BibTeX

13.

Ramos-Rodríguez, Carla; Rojas-Gomez, Alejandra; Santos-Calderón, Luis A; Ceruelo, Santiago; Ríos, Lídia; Ueland, Per M; Fernandez-Ballart, Joan D; Salas-Huetos, Albert; Murphy, Michelle M

The l-Arginine pathway may act as a mediator in the association between impaired one-carbon metabolism and hypertension Journal Article

In: Biochimie, vol. 230, pp. 86–94, 2025, ISSN: 1638-6183.

Abstract | Links | BibTeX

14.

Svenningsson, Mads M; Svingen, Gard Ft; Ueland, Per M; Sulo, Gerhard; Bjørnestad, Espen Ø; Pedersen, Eva R; Dhar, Indu; Nilsen, Dennis W; Nygård, Ottar

Elevated plasma trimethyllysine is associated with incident atrial fibrillation Journal Article

In: Am J Prev Cardiol, vol. 21, pp. 100932, 2025, ISSN: 2666-6677.

Abstract | Links | BibTeX

15.

Damerell, Victoria; Klaassen-Dekker, Niels; Brezina, Stefanie; Ose, Jennifer; Ulvik, Arve; van Roekel, Eline H; Holowatyj, Andreana N; Baierl, Andreas; Böhm, Jürgen; Bours, Martijn J L; Brenner, Hermann; de Wilt, Johannes H W; Grady, William M; Habermann, Nina; Hoffmeister, Michael; Keski-Rahkonen, Pekka; Lin, Tengda; Schirmacher, Peter; Schrotz-King, Petra; Ulrich, Alexis B; van Duijnhoven, Fränzel J B; Warby, Christy A; Shibata, David; Toriola, Adetunji T; Figueiredo, Jane C; Siegel, Erin M; Li, Christopher I; Gsur, Andrea; Kampman, Ellen; Schneider, Martin; Ueland, Per M; Weijenberg, Matty P; Ulrich, Cornelia M; Kok, Dieuwertje E; and, Biljana Gigic

Circulating tryptophan-kynurenine pathway metabolites are associated with all-cause mortality among patients with stage I-III colorectal cancer Journal Article

In: Int J Cancer, vol. 156, no. 3, pp. 552–565, 2025, ISSN: 1097-0215.

Abstract | Links | BibTeX

16.

Fossdal, Guri; Braadland, Peder; Hov, Johannes Roksund; Husebye, Eystein Sverre; Folseraas, Trine; Ueland, Per Magne; Ulvik, Arve; Karlsen, Tom Hemming; Berge, Rolf Kristian; Vesterhus, Mette

Mitochondrial dysfunction and lipid alterations in primary sclerosing cholangitis Journal Article

In: Scand J Gastroenterol, vol. 60, no. 2, pp. 165–173, 2025, ISSN: 1502-7708.

Abstract | Links | BibTeX

17.

Walzik, David; Joisten, Niklas; Schenk, Alexander; Trebing, Sina; Schaaf, Kirill; Metcalfe, Alan J; Spiliopoulou, Polyxeni; Hiefner, Johanna; McCann, Adrian; Watzl, Carsten; Ueland, Per Magne; Gehlert, Sebastian; Worthmann, Anna; Brenner, Charles; Zimmer, Philipp

Acute exercise boosts NAD metabolism of human peripheral blood mononuclear cells Journal Article

In: Brain Behav Immun, vol. 123, pp. 1011–1023, 2025, ISSN: 1090-2139.

Abstract | Links | BibTeX

18.

Santos-Calderón, Luis A; Cavallé-Busquets, Pere; Ramos-Rodríguez, Carla; Grifoll, Carme; Rojas-Gómez, Alejandra; Ballesteros, Mónica; Ueland, Per M; Murphy, Michelle M

Folate and cobalamin status, indicators, modulators, interactions, and reference ranges from early pregnancy until birth: the Reus-Tarragona birth cohort study Journal Article

In: Am J Clin Nutr, vol. 120, no. 5, pp. 1269–1283, 2024, ISSN: 1938-3207.

Abstract | Links | BibTeX

19.

Anfinsen, Åslaug Matre; Myklebust, Vilde Haugen; Johannesen, Christina Osland; Christensen, Jacob Juel; Laupsa-Borge, Johnny; Dierkes, Jutta; Nygård, Ottar; McCann, Adrian; Rosendahl-Riise, Hanne; Lysne, Vegard

Serum concentrations of lipids, ketones and acylcarnitines during the postprandial and fasting state: the Postprandial Metabolism (PoMet) study in healthy young adults Journal Article

In: Br J Nutr, vol. 132, no. 7, pp. 851–861, 2024, ISSN: 1475-2662.

Abstract | Links | BibTeX

20.

Holthuijsen, Daniëlle D B; van Roekel, Eline H; Bours, Martijn J L; Ueland, Per M; Breukink, Stéphanie O; Janssen-Heijnen, Maryska L G; Keulen, Eric T P; Brezina, Stefanie; Gigic, Biljana; Peoples, Anita R; Ulrich, Cornelia M; Ulvik, Arve; Weijenberg, Matty P; Eussen, Simone J P M

Longitudinal associations of plasma kynurenines and ratios with fatigue and quality of life in colorectal cancer survivors up to 12 months post-treatment Journal Article

In: Int J Cancer, vol. 155, no. 7, pp. 1172–1190, 2024, ISSN: 1097-0215.

Abstract | Links | BibTeX

562 entries « 1 of 29 »

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