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Four pre-designed panels for targeted biomarker studies of cardiometabolic functions, inflammation and immune activation, gut microbiome health, nutritional and lifestyle.
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Precision Panels. Tailored Solutions.
Bevital`s four targeted metabolomic panels — cardiometabolic, inflammation, microbiome, and nutrition — allow customers to choose between pre-designed solutions at low costs. The panels have been designed to be analytically and biologically complementary and are established across dedicated GC- and LC-MS/MS platforms. This allows quantification of diverse, but related classes of both high- and low-abundance metabolites. Turn-around time is about 2-6 weeks depending on number of samples and laboratory capacity. Typical sample material is EDTA plasma, serum, or CSF.
The four analytical panels are highly interrelated, as many diseases involve interactions across these metabolic domains. Together, they provide a comprehensive view of an individual’s health status, allowing for more precise diagnosis, management, and monitoring. Combining these panels allows researchers and clinicians to identify interconnected pathways contributing to complex, multifaceted diseases.
Cardiometabolic & Inflammation
Many cardiometabolic diseases, such as cardiovascular disease, diabetes, and metabolic syndrome, involve chronic inflammation. Assessing both metabolic and inflammatory biomarkers enables clinicians to understand disease risk and monitor therapeutic responses, targeting both metabolic control and inflammation.
Microbiome & Nutrition
The microbiome affects nutrient absorption and metabolism, influencing overall nutritional status. This relationship is especially relevant for gastrointestinal disorders, obesity, and autoimmune diseases where gut health can impact inflammation and nutrient bioavailability. By combining microbiome and nutritional panels, clinicians can optimize dietary interventions and support gut health.
Cardiometabolic & Nutrition
Dietary intake and nutritional balance directly impact cardiometabolic health, affecting risk factors for obesity, hypertension, and dyslipidemia. By evaluating nutritional biomarkers alongside cardiometabolic markers, clinicians can offer personalized dietary recommendations.
Inflammation & Microbiome
The gut microbiome has a significant influence on systemic inflammation, impacting conditions such as autoimmune diseases, metabolic syndrome, and inflammatory bowel disease. Assessing both microbiome and inflammatory markers can provide insights into the inflammatory responses driven by gut health and guide targeted interventions.
Acylcarnitines: BB, C0, C2, C3, C3-DC, C4, C4-OH, C4-DC, iC5, C5-DC, C5:1, C6, C8, C10, C12, C14, C14-OH, C16, C16-OH, C18, C18-OH, C18:1, C18:2
AGEs: Carboxyethyllysine, Carboxymethyllysine
Amino acids: Alanine, Arginine, Asparagine, Aspartic acid, Glutamic acid, Glutamine, Glycine, Histidine, Isoleucine, Kynurenine, Leucine, Lysine, Methionine, Ornithine, Phenylalanine, Proline, Sarcosine, Serine, Threonine, Total cysteine, Tryptophan, Tyrosine, Valine
Amino acid catabolites: 2-Aminoadipic acid, 2-Hydroxybutyrate, 3-Hydroxysiobutyrate, α-Hydroxyglutaric acid, β-Alanine, β-Aminoisobutyrate, β-Hydroxy β-methylbutyric acid, Phenylacetylglutamine
Ketone bodies: Acetoacetate, 3-Hydroxybutyrate
TCA metabolites: α-Ketoglutarate, Citrate, Fumarate, Isocitrate, Lactate, Malate, Pyruvate
Kynurenines: 3-hydroxykynurenine, 3-hydroxyanthranilic acid, Anthranilic acid, Kynurenine, Kynurenic acid, Nicotinic acid, Nicotinamide, N1-methylnicotinamide, Picolinic acid, Quinaldic acid, Quinolinic acid, Xanthurenic acid
Ratio-derived: Kynurenine/tryptophan ratio, PAr index (PLP, PL, PA)
Neopterin
Proteins: Under development
Amino acid derived: Phenylacetylglutamine
Choline metabolites: Betaine, Choline, DMG, TMAO
Indoles: 3-Indoxyl sulfate, Imidazole propionate, Indole-3-acetamide, Indole-3-acetate, Indole-3-aldehyde, Indole-3-lactate, Indole-3-propionate
SCFAs: Acetate, Butyrate, Formate, Isobutyrate, Isovalerate, Propionate, Valerate, α-Methylbutyrate
B-vitamins, functional markers, and methyl donors: Betaine, Choline, Cobalamin, Flavin mononucleotide, Folate, Methylmalonic acid, N1-Methylnicotinamide, Nicotinamide, Nicotinic acid, Pyridoxal, 4-Pyridoxic acid, Pyridoxal 5-phosphate, Pyridoxine, Riboflavin, Thiamine, Thiamine monophosphate, Total homocysteine
Essential amino acids: Histidine, Isoleucine, Leucine, Lysine, Methionine, Phenylalanine, Threonine, Tryptophan, Valine
Fat-soluble vitamins: 25-Hydroxy vitamin D2, 25-Hydroxy vitamin D3, α-Tocopherol (Vit. E), All-trans retinol (Vit. A), Phylloquinone (Vit. K1), y-Tocopherol (Vit. E)
Meat and fish intake: 1-Methylhistidine, 3-Methylhistidine, β-Alanine, Creatine, Creatinine, TMAO
Tobacco use and coffee intake: Cotinine, Trans-3-hydroxycotinine, Trigonelline
Acylcarnities: BB, C0, C2, C3, C3-DC, C4, C4-OH, C4-DC, iC5, C5-DC, C5:1, C6, C8, C10, C12, C14, C14-OH, C16, C16-OH, C18, C18-OH, C18:1, C18:2
AGEs: Carboxyethyllysine, Carboxymethyllysine
Amino acids: Alanine, Arginine, Asparagine, Aspartic acid, Glutamic acid, Glutamine, Glycine, Histidine, Isoleucine, Kynurenine, Leucine, Lysine, Methionine, Ornithine, Phenylalanine, Proline, Sarcosine, Serine, Threonine, Total cysteine, Tryptophan, Tyrosine, Valine
Amino acid catabolites: 2-Aminoadipic acid, 2-Hydroxybutyrate, 3-Hydroxysiobutyrate, α-Hydroxyglutaric acid, β-Alanine, β-Aminoisobutyrate, β-Hydroxy β-methylbutyric acid, Phenylacetylglutamine
Ketone bodies: Acetoacetate, 3-Hydroxybutyrate
TCA metabolites: α-Ketoglutarate, Citrate, Fumarate, Isocitrate, Lactate, Malate, Pyruvate
Kynurenines: 3-hydroxykynurenine, 3-hydroxyanthranilic acid, Anthranilic acid, Kynurenine, Kynurenic acid, Nicotinic acid, Nicotinamide, N1-methylnicotinamide, Picolinic acid, Quinaldic acid, Quinolinic acid, Xanthurenic acid
Neopterin
Ratio-derived: Kynurenine/tryptophan ratio, PAr index (PLP, PL, PA)
Proteins: Under development
Amino acid derived: Phenylacetylglutamine
Choline metabolites: Choline, Betaine, DMG, TMAO
Indoles: 3-Indoxyl sulfate, Imidazole propionate, Indole-3-acetamide, Indole-3-acetate, Indole-3-aldehyde, Indole-3-lactate, Indole-3-propionate
SCFAs: Acetate, Butyrate, Formate, Isobutyrate, Isovalerate, Propionate, Valerate, α-Methylbutyrate
B-vitamins, functional markers, and methyl donors: Betaine, Choline, Cobalamin, Flavin mononucleotide, Folate, Methylmalonic acid, N1-methylnicotinamide, Nicotinamide, Nicotinic acid, Pyridoxal, 4-Pyridoxic acid, Pyridoxal 5-phosphate, Pyridoxine, Riboflavin, Thiamine, Thiamine monophosphate, Total homocysteine
Fat-soluble vitamins: 25-Hydroxy vitamin D2, 25-Hydroxy vitamin D3, α-Tocopherol (Vit. E), All-trans retinol (Vit. A), Phylloquinone (Vit. K1), y-Tocopherol (Vit. E)
Essential amino acids: Histidine, Isoleucine, Leucine, Lysine, Methionine, Phenylalanine, Threonine, Tryptophan, Valine
Meat and fish intake: 1-Methylhistidine, 3-Methylhistidine, β-Alanine, Creatine, Creatinine, TMAO
Tobacco use and coffee intake: Cotinine, Trans-3-hydroxycotinine, Trigonelline
