Assessment of Disease Risk by Targeted Metabolomics
Vitamins & Lifestyle
B vitamins, folate and cobalamin, fat soluble vitamins, tobacco and coffee, meat and fish intake.
Metabolites & Pathways
AGEs, amino acids and metabolites, acylcarnitines, choline oxidation pathway, citric acid cycle, microbiota derived, one carbon metabolism, transsulfuration, tryptophan metabolites, urea cycle, others.
Pathologies & Physiology
Diabetes, endothelial function, inflammation, keton bodies, liver pathology, neuroactive, oncometabolites, renal function, uremic toxin.
GC-MS/MS
A: Short-chain fatty acids.
B: Amino and carboxylic acids. TCA metabolites and intermediates.
LC-MS/MS
C: Choline derivatives. Charged, methylated or sulfur amino acids.
Short-chain acylcarnitines.
D: Kynurenine pathway and B vitamins.
E: Folate species and catabolites.
H: Lipid-soluble vitamins and long-chain acylcarnitines.
I: Short-, medium-, and long-chain acylcarnitines (under development).
MALDI-TOF MS
G: Protein biomarkers (C-reactive protein, serum amyloid A, calprotectin, cystatin C) and their proteoforms. HbA1c.
Microbiological assay
F: Folate and cobalamin.
Our Services
Platform selection
Choice of biomarker panels and analytical platforms can be crucial for the project outcome. Our experts will help you by a pre-analytical evaluation to maximise data quality and quantity at minimal sample consumption.
Data report
Customers receive a detailed report including metabolite concentrations, LODs, missing data diagnosis, quality controls, CVs, and basic data plots.
Data analysis
We offer academic support by our scientists using sophisticated statistical methods based on R and Shiny apps.
Literature
Our website provides detailed information about all offered biomarkers, metabolites and pathways, and pre-analytical stability including pdfs of scientific articles.