BEVITAL AS

High-Precision Metabolomics

and Proteomics

Targeted Omics for Reliable Biomarker Quantification. For Scientists from Scientists.

High-Precision Metabolomics

and Proteomics

Targeted Omics for Reliable Biomarker Quantification. For Scientists from Scientists.

High-Precision Metabolomics

and Proteomics

Targeted Omics for Reliable Biomarker Quantification. For Scientists from Scientists.
High-precision Metabolomics
High-precision Metabolomics

Bevital´s metabolomics platforms have been designed using authentic isotope-labelled internal standards for each analyte, providing highest precision and reliability for targeted metabolomics or validation studies of untargeted approaches.

Physiological Concentration Ranges
Physiological Concentration Ranges

Bevital´s diverse analytical platforms allow biomarker quantification at physiologically relevant wide dynamic ranges from pmol/L to mmol/L. Hence, Bevital´s metabolomics methods typically deliver very low numbers of missing data.

Highly Reliable Quantification
Highly Reliable Quantification

Bevital´s methods provide highly accurate reproducible quantification. Participation in external programs as DEKS, DEQAS, KEQAS, ERNDIM and LABQUALITY are a part of our quality control to assure highest quality from sample storage to data delivery.

Complete Metabolomic Pathways
Complete Metabolomic Pathways

Bevital´s pathway panels include dietary biomarkers, metabolic intermediates, vitamins, and derived co-factors, offering a comprehensive view of the targeted metabolomics network, including potential avenues for crosstalk with other pathways.

Full Academic Support
Full Academic Support

Bevital has been involved in numerous scientific projects and can provide academic support from writing of funding applications, statistical data analysis, to critical review of draft manuscripts.

20+ Years of Experience
20+ Years of Experience

Bevital´s staff has long experience in development of bio-analytical technologies and their application in large epidemiological projects. Bevital´s workflow guarantees optimal sample handling with respect to sample matrix, pre-analytical stability and sample consumption.

Satisfied collaborators and customers
Satisfied collaborators and customers

HUNT Research Centre

Department of Public Health and Nursing,
NTNU, Norway

"HUNT Research Centre, Department of Public Health and Nursing, NTNU, has been involved in an international consortium in cancer research (LC3). Relevant biomarkers were analyzed by Bevital. We are very satisfied with the collaboration with the laboratory, they had thorough quality procedures, deliveries as agreed upon, in addition to helpful contributions to quality classification of blood samples of HUNT participants."

Allison Hodge

Principal Research Fellow,
Cancer Epidemiology Division,
Cancer Council Victoria, Australia

"I have worked with colleagues at Bevital for many years looking at biomarkers associated with health and potentially cancer in the Melbourne Collaborative Cohort Study. The scientists at Bevital are great to work with in terms of contributing to study design (selecting which markers to measure) and grant applications, analysing the results and writing these up. They have the expertise to complement our epidemiological skills. Logistically, sending samples from Australia has not caused any issues and the whole process of sending samples and receiving our data has gone smoothly. The costs are fair, especially in a collaborative arrangement where we benefit more from Bevital’s experience and the data can be put to additional use by the Bevital team."

Allison Hodge

Principal Research Fellow
Cancer Epidemiology Division
Cancer Council Victoria

"I have worked with colleagues at Bevital for many years looking at biomarkers associated with health and potentially cancer in the Melbourne Collaborative Cohort Study. The scientists at Bevital are great to work with in terms of contributing to study design (selecting which markers to measure) and grant applications, analysing the results and writing these up. They have the expertise to complement our epidemiological skills. Logistically, sending samples from Australia has not caused any issues and the whole process of sending samples and receiving our data has gone smoothly. The costs are fair, especially in a collaborative arrangement where we benefit more from Bevital’s experience and the data can be put to additional use by the Bevital team."

HUNT Research Centre

Department of Public Health and Nursing,
NTNU, Norway

"HUNT Research Centre, Department of Public Health and Nursing, NTNU, has been involved in an international consortium in cancer research (LC3). Relevant biomarkers were analyzed by Bevital. We are very satisfied with the collaboration with the laboratory, they had thorough quality procedures, deliveries as agreed upon, in addition to helpful contributions to quality classification of blood samples of HUNT participants."

Allison Hodge

Principal Research Fellow,
Cancer Epidemiology Division,
Cancer Council Victoria, Australia

"I have worked with colleagues at Bevital for many years looking at biomarkers associated with health and potentially cancer in the Melbourne Collaborative Cohort Study. The scientists at Bevital are great to work with in terms of contributing to study design (selecting which markers to measure) and grant applications, analysing the results and writing these up. They have the expertise to complement our epidemiological skills. Logistically, sending samples from Australia has not caused any issues and the whole process of sending samples and receiving our data has gone smoothly. The costs are fair, especially in a collaborative arrangement where we benefit more from Bevital’s experience and the data can be put to additional use by the Bevital team."

Allison Hodge

Principal Research Fellow
Cancer Epidemiology Division
Cancer Council Victoria

"I have worked with colleagues at Bevital for many years looking at biomarkers associated with health and potentially cancer in the Melbourne Collaborative Cohort Study. The scientists at Bevital are great to work with in terms of contributing to study design (selecting which markers to measure) and grant applications, analysing the results and writing these up. They have the expertise to complement our epidemiological skills. Logistically, sending samples from Australia has not caused any issues and the whole process of sending samples and receiving our data has gone smoothly. The costs are fair, especially in a collaborative arrangement where we benefit more from Bevital’s experience and the data can be put to additional use by the Bevital team."

Metabolomics

Ready-to-Run

Cardiometabolic


65 biomarkers from 200μl sample


Amino acids and catabolites, acylcarnitines, TCA metabolites, ketone bodies, AGEs

Inflammation& Immune Activation


19 biomarkers from 150μl sample


Kynurenines and ratio-derived metabolites, Neopterin, CRP, serum amyloid A, calprotectin

Microbiome


20 biomarkers from 250μl sample


SCFAs, indoles, choline oxidation, amino acid derived metabolites


Nutritional Status& Lifestyle


41 biomarkers from 300μl sample


B-vitamins, fat-soluble vitamins, essential amino acids, meat & fish intake, tobacco use & coffee intake

Cardiometabolic


65 biomarkers from 200μl sample


Amino acids and catabolites, acylcarnitines, TCA metabolites, ketone bodies, AGEs

Inflammation& Immune Activation


19 biomarkers from 150μl sample


Kynurenines and ratio-derived metabolites, Neopterin, CRP, serum amyloid A, calprotectin

Microbiome


20 biomarkers from 250μl sample


SCFAs, indoles, choline oxidation, amino acid derived metabolites


Nutritional Status& Lifestyle


41 biomarkers from 300μl sample


B-vitamins, fat-soluble vitamins, essential amino acids, meat & fish intake, tobacco use & coffee intake

Metabolomics

Mix-and-Match

Bevital offers to combine any biomarker of the analytical repertoire with other markers and panels to provide the flexibility customers require for their projects. Contact us to discuss your project and learn more about our complementary analytical platforms.

  • Acylcarnitines
  • AGEs
  • Amino acids & metabolites
  • B-vitamins
  • Fat-soluble vitamins
  • Meat & fish intake
  • Microbiota derived
  • Tobacco & coffee
  • Choline oxidation
  • One-carbon metabolism
  • Transsulfuration
  • Tricarboxylic acid cycle
  • Tryptophan metabolism
  • Urea cycle
  • Diabetes
  • Endothelial function
  • Inflammation
  • Ketone bodies
  • Liver disease
  • Neuroactive metabolites
  • Oncometabolites
  • Renal function
  • Uremic toxins

Bevital offers to combine any biomarker of the analytical repertoire with other markers and panels to provide the flexibility customers require for their projects. Contact us to discuss your project and learn more about our complementary analytical platforms.

  • Acylcarnitines
  • AGEs
  • Amino acids & metabolites
  • B-vitamins
  • Fat-soluble vitamins
  • Meat & fish intake
  • Microbiota derived
  • Tobacco & coffee
  • Choline oxidation
  • One-carbon metabolism
  • Transsulfuration
  • Tricarboxylic acid cycle
  • Tryptophan metabolism
  • Urea cycle
  • Diabetes
  • Endothelial function
  • Inflammation
  • Ketone bodies
  • Liver disease
  • Neuroactive metabolites
  • Oncometabolites
  • Renal function
  • Uremic toxins
Metabolomics

Customized Analyses

Not Found What You Are Looking For?

Biomarkers not listed in Bevital´s analytical repertoire may be included into existing panels and be analysed by customized assays. Contact our experts to discuss your needs and the strategies to realize your project. Project evaluation has to include:

  • Classes and types of compounds
  • Number of samples
  • Sample matrix
  • Time frame
  • Published analytical methods
Proteomics

Olink®

Benefit From Our In-house Proteomics

Bevital is a service provider of Olink® and offers 16 different Olink® Target 96&48 panels for high-quality proteomics.

For larger flexibility ~200 proteins can be combined in Olink® Flex panels, offering up to 21 assays in 40 samples per kit.

Our recent webinar
Introducing next-generation proteomics to your multi-omics studies: novel insights into inflammation and immune activation” 
gives you more insight into Olink´s technologies and their application in multi-omics approaches.

Omics

Biogenity

Bevital is a contract partner of Biogenity, a Research Organisation specialized in omics research and discovery. With Biogenity as strong partner in biostatistics, Bevital can offer a streamlined workflow from planning of multi-omics projects to data integration and interpretation. Furthermore, collaboration with Biogenity allows our customers to add several omics as transcriptomics and genomics data to their projects.

Biogenity offers different types of data analysis as

  • Data cleaning and visualization
  • Statistical analysis
  • Bioinformatical analysis
  • AI powered data analysis
  • Peptide and protein annotation
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Cardiometabolic
Inflammation
Microbiome
Nutrition
Categories

Amino acids, amino acid catabolites, acylcarnitines, TCA metabolites, ketone bodies, AGEs



Kynurenines, ratio-derived metabolites, proteins





SCFAs, indoles, choline metabolites, amino acid derived





B-vitamins, functional markers, and methyl donors, fat-soluble vitamins, essential amino acids, meat & fish intake, tobacco use & coffee intake
Biomarkers (n)
65
19
20
41
View

Amino acids: Alanine, Arginine, Asparagine, Aspartic acid, Glutamic acid, Glutamine, Glycine, Histidine, Isoleucine, Kynurenine, Leucine, Lysine, Methionine, Ornithine, Phenylalanine, Proline, Sarcosine, Serine, Threonine, Total cysteine, Tryptophan, Tyrosine, Valine

Amino acid catabolites: 2-Aminoadipic acid, 2-Hydroxybutyrate, 3-Hydroxysiobutyrate, α-Hydroxyglutaric acid, β-Alanine, β-Aminoisobutyrate, β-Hydroxy B-methylbutyric acid, Phenylacetylglutamine

Acylcarnities: BB, C0, C2, C3, C3-DC, C4, C4-OH, C4-DC, iC5, C5-DC, C5:1, C6, C8, C10, C12, C14, C14-OH, C16, C16-OH, C18, C18-OH, C18:1, C18:2

TCA metabolites: α-Ketoglutarate, Citrate, Fumarate, Isocitrate, Lactate, Malate, Pyruvate

Ketone bodies: Acetoacetate, 3-Hydroxybutyrate

AGEs: Carboxyethyllysine, Carboxymethyllysine

View

Kynurenines: 3-hydroxykynurenine, 3-hydroxyanthranilic acid, Anthranilic acid, Kynurenine, Kynurenic acid, Nicotinic acid, Nicotinamide, N1-methylnicotinamide, Picolinic acid, Quinaldic acid, Quinolinic acid, Xanthurenic acid

Neopterin

Proteins: C-Reactive protein, Calprotectin, Serum Amyloid A

Ratio-derived: Kynurenine/tryptophan ratio, PAr index (PLP, PL, PA)

View

SCFAs: Acetate, Butyrate, Formate, Isobutyrate, Isovalerate, Propionate, Valerate, α-Methylbutyrate

Indoles: 3-Indoxyl sulfate, Imidazole propionate, Indole-3-acetamide, Indole-3-acetate, Indole-3-aldehyde, Indole-3-lactate, Indole-3-propionate

Choline metabolites: Choline, Betaine, DMG, TMAO

Amino acid derived: Phenylacetylglutamine

View

B-vitamins, functional markers, and methyl donors: 4-Pyridoxic acid, Betaine, Choline, Cobalamin, Flavin mononucleotide, Folate, Methylmalonic acid, N1-methylnicotinamide, Nicotinamide, Nicotinic acid, Pyridoxal, Pyridoxal 5-phosphate, Pyridoxine, Riboflavin, Thiamine, Thiamine monophosphate, Total homocysteine

Fat-soluble vitamins: 25-hydroxy vitamin D2, 25-hydroxy vitamin D3, α-Tocopherol (Vit. E), All-trans retinol (Vit. A), Phylloquinone (Vit. K1), y-Tocopherol (Vit. E)

Essential amino acids: Histidine, Isoleucine, Leucine, Lysine, Methionine, Phenylalanine, Threonine, Tryptophan, Valine

Meat and fish intake: 1-Methylhistidine, 3-Methylhistidine, B-Alanine, Creatine, Creatinine, TMAO

Tobacco use and coffee intake: Cotinine, Trans-3-hydroxycotinine, Trigonelline

Volume (μl)
200
150
250
300
Analytical techniques
GC- and LC-MS/MS
LC- and MALDI-MS
GC- and LC-MS/MS
GC- and LC-MS/MS
Turnaround time (weeks)
1
1
1
1

Olink Proteomics

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Customized analyses

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Mix-and-Match

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Ready-to-Run

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