BEVITAL AS

High-Precision Metabolomics

& Proteomics


Decoding Metabolism’s Impact on Health, Disease and Quality of Life
& Proteomics

High-Precision Metabolomics


Decoding Metabolism's Impact on Health, Disease and Quality of Life

From Scientists for Scientists

High-Precision Metabolomics

Bevital´s analytical platforms are designed with authentic isotope-labelled internal standards for each analyte, ensuring the highest precision, reliability and statistical power for targeted metabolomics and validation studies.

Physiological Concentration Ranges

Bevital’s diverse analytical platforms allow quantification at physiologically relevant dynamic ranges from pmol/L to mmol/L in various sample matrices as serum, plasma or CSF. Consequently, Bevital’s metabolomics methods typically result in very few missing data points.

Highly Reliable Quantification

Bevital’s methods ensure highly accurate and reproducible quantification. Our participation in external programs as DEKS, DEQAS, KEQAS, ERNDIM and LABQUALITY are part of our quality control, guaranteeing the highest standards from sample storage to data delivery.

Complete Metabolomic Pathways

Bevital’s pathway panels include dietary biomarkers, metabolic intermediates, vitamins, and derived co-factors, offering a comprehensive view of the targeted metabolomics network, including potential avenues for crosstalk with other pathways.

Full Academic Support

Bevital has been involved in numerous scientific projects and can provide academic support from writing of funding applications, statistical data analysis, to critical review of draft manuscripts.

20+ Years of Experience

Bevital’s staff has extensive experience in developing bio-analytical technologies and applying them in large epidemiological projects. Our workflow ensures optimal sample handling, taking into account pre-analytical stability, matrix effects and minimizing sample consumption.

Metabolomics

Ready-to-Run

Bevital’s analytical repertoire has been thoughtfully and strategically developed, focusing on established biomarkers, specific metabolites, metabolic classes, and key pathways. We offer four pre-designed analytical panels addressing cardiometabolic functions, inflammation and immune activation, gut microbiome health, nutritional and lifestyle markers.

Cardiometabolic

•Acylcarnitines
•AGEs
•Amino acids and catabolites
•Ketone bodies
•TCA metabolites

Inflammation & Immune Activation

•Kynurenines and ratio-derived metabolites
•Neopterin
•Proteins: Calprotectin, CRP, serum amyloid A

Microbiome

•Amino acid derived metabolites
•Choline oxidation
•Indoles
•SCFAs

Nutritional Status & Lifestyle

•B- and fat- soluble vitamins
•Essential amino acids
•Meat & fish intake
•Tobacco use & coffee intake


Cardiometabolic

•Acylcarnitines
•AGEs
•Amino acids and catabolites
•Ketone bodies
•TCA metabolites

Inflammation &
Immune Activation

•Kynurenines and ratio-derived metabolites
•Neopterin
•Proteins: Calprotectin, CRP, SAA



Microbiome

•Amino acid derived metabolites
•Choline oxidation
•Indoles
•SCFAs


Nutritional Status &
Lifestyle

•B- and fat- soluble vitamins
•Essential amino acids
•Meat & fish intake
•Tobacco use & coffee intake


Mix-and-Match

Metabolites, intermediates, vitamins, and co-factors are organized into various categories and can be combined with any individual marker or panel, offering maximum flexibility for your project. Bevital’s methods have been thoroughly validated and published in high-impact journals.

Full flexibility

Not Found What You Are Looking For?

Analytes not listed in our analytical repertoire may be included into existing panels and be analysed by customized assays. Contact our experts to discuss your needs and the strategies to realize your project. Project evaluation should include:

  • Classes and types of compounds
  • Number of samples
  • Sample matrix
  • Time frame
  • Published analytical methods

Multiomics Services

Bevital is a service provider of Olink® and offers 16 different Olink® Target 96&48 panels for high-quality proteomics from 1 µl of sample volume only.

For larger flexibility customers can choose from about 200 proteins and combine them in unique Olink® Flex panels, offering 5 to 30 assays per kit.

Bevital partners with Biogenity, a research organization specializing in omics research and discovery. With Biogenity’s expertise in biostatistics, Bevital provides a seamless workflow from multi-omics project planning to data integration and interpretation. This collaboration enables our customers to expand their projects by incorporating additional omics data, such as transcriptomics and genomics.

Testimonials

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Learn more about our new NAD and Bile Acids panels!

562 entries « 1 of 29 »
1.

Bakker, Lieke; Ramakers, Inez H G B; van Greevenbroek, Marleen M J; Backes, Walter H; Jansen, Jacobus F A; Schram, Miranda T; van der Kallen, Carla J H; Schalkwijk, Casper G; Wesselius, Anke; Ulvik, Arve; Ueland, Per M; Verhey, Frans R J; Eussen, Simone J P M; Köhler, Sebastian

The kynurenine pathway and markers of neurodegeneration and cerebral small vessel disease: The Maastricht Study Journal Article

In: J Neurol Sci, vol. 474, pp. 123522, 2025, ISSN: 1878-5883.

Abstract | Links | BibTeX

2.

Holthuijsen, Daniëlle D B; van Roekel, Eline H; Bours, Martijn J L; Ueland, Per M; Breukink, Stéphanie O; Janssen-Heijnen, Maryska L G; Konsten, Joop L; Keulen, Eric T P; McCann, Adrian; Brezina, Stefanie; Gigic, Biljana; Kok, Dieuwertje E; Ulrich, Cornelia M; Weijenberg, Matty P; Eussen, Simone J P M

Modeling how iso-caloric macronutrient substitutions are longitudinally associated with plasma kynurenines in colorectal cancer survivors up to 12 months post-treatment Journal Article

In: J Nutr Biochem, vol. 141, pp. 109910, 2025, ISSN: 1873-4847.

Abstract | Links | BibTeX

3.

Belen, Sergen; Patt, Nadine; Kupjetz, Marie; Ueland, Per M; McCann, Adrian; Gonzenbach, Roman; Bansi, Jens; Zimmer, Philipp

Vitamin B status is related to disease severity and modulated by endurance exercise in individuals with multiple sclerosis: a secondary analysis of a randomized controlled trial Journal Article

In: Am J Clin Nutr, vol. 121, no. 6, pp. 1403–1414, 2025, ISSN: 1938-3207.

Abstract | Links | BibTeX

4.

Dahl, Tuva B; Aftab, Friha; Prebensen, Christian; Berdal, Jan-Erik; Ueland, Thor; Barratt-Due, Andreas; Riise, Anne Ma Dyrhol; Ueland, Per Magne; Hov, Johannes R; Trøseid, Marius; Aukrust, Pål; Gregersen, Ida; Myhre, Peder L; Omland, Torbjørn; Halvorsen, Bente

Imidazole propionate is increased in severe COVID-19 and correlates with cardiac involvement Miscellaneous

2025, ISSN: 1532-2742.

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5.

Banjara, Sarala; Berggreen, Ellen; Igland, Jannicke; Åstrøm, Anne-Kristine; Midttun, Øivind; Bunæs, Dagmar; Sulo, Gerhard

Plasma levels of immune system activation markers Neopterin and Kynurenine-to-Tryptophan Ratio, and oral health among community-dwelling adults in Norway: a population-based, cohort study Journal Article

In: Acta Odontol Scand, vol. 84, pp. 218–225, 2025, ISSN: 1502-3850.

Abstract | Links | BibTeX

6.

Holthuijsen, Daniëlle D B; Rijnhart, Judith J M; Bours, Martijn J L; van Roekel, Eline H; Ueland, Per M; Breukink, Stéphanie O; Janssen-Heijnen, Maryska L G; Konsten, Joop L; Keulen, Eric T P; McCann, Adrian; Brezina, Stefanie; Gigic, Biljana; Ulrich, Cornelia M; Weijenberg, Matty P; Eussen, Simone J P M

Longitudinal associations of dietary intake with fatigue in colorectal cancer survivors up to 1 year post-treatment, and the potential mediating role of the kynurenine pathway Journal Article

In: Brain Behav Immun, vol. 126, pp. 144–159, 2025, ISSN: 1090-2139.

Abstract | Links | BibTeX

7.

Joisten, Niklas; Reuter, Marcel; Rosenberger, Friederike; Venhorst, Andreas; Kupjetz, Marie; Walzik, David; Schenk, Alexander; McCann, Adrian; Ueland, Per Magne; Meyer, Tim; Zimmer, Philipp

Exercise training restores longevity-associated tryptophan metabolite 3-hydroxyanthranilic acid levels in middle-aged adults Journal Article

In: Acta Physiol (Oxf), vol. 241, no. 5, pp. e70041, 2025, ISSN: 1748-1716.

Abstract | Links | BibTeX

8.

Jørgensen, Silje F; Braadland, Peder R; Ueland, Thor; Fraz, Mai S A; Michelsen, Annika E; Holm, Kristian; Osnes, Liv T; Trøseid, Marius; Ueland, Per Magne; Fevang, Børre; Aukrust, Pål; Hov, Johannes R

Tryptophan-kynurenine metabolites associate with inflammation and immunologic phenotypes in common variable immunodeficiency Journal Article

In: J Allergy Clin Immunol, 2025, ISSN: 1097-6825.

Abstract | Links | BibTeX

9.

Grytten, Elise; Laupsa-Borge, Johnny; Cetin, Kaya; Bohov, Pavol; Nordrehaug, Jan Erik; Skorve, Jon; Berge, Rolf K; Strand, Elin; Bjørndal, Bodil; Nygård, Ottar K; Rostrup, Espen; Mellgren, Gunnar; Dankel, Simon N

Inflammatory markers after supplementation with marine n-3 or plant n-6 PUFAs: A randomized double-blind crossover study Journal Article

In: J Lipid Res, vol. 66, no. 4, pp. 100770, 2025, ISSN: 1539-7262.

Abstract | Links | BibTeX

10.

Trollebø, Marte A; Tangvik, Randi J; Skeie, Eli; Nygård, Ottar; Eagan, Tomas M L; McCann, Adrian; Dierkes, Jutta

Metabolic profiles and malnutrition in hospitalized adults: A metabolomic cohort study Journal Article

In: JPEN J Parenter Enteral Nutr, vol. 49, no. 3, pp. 365–372, 2025, ISSN: 1941-2444.

Abstract | Links | BibTeX

11.

Valim, Valéria; Oliveira, Fabíola R; Miyamoto, Samira T; Serrano, Érica V; Balarini, Gabriela M; Tanure, Leandro A; Ferreira, Gilda A; Zandonade, Eliana; Brun, Johan G; Jonsson, Malin; Maeland, Elisabeth; Ulvik, Arve; Ueland, Per Magne; Jonsson, Roland; Mydel, Piotr M

Kynurenines and neopterin are interferon-gamma-inducible biomarkers for Sjögren's disease Journal Article

In: Rheumatology (Oxford), 2025, ISSN: 1462-0332.

Abstract | Links | BibTeX

12.

Wilson, Edward N; Umans, Jacob; Swarovski, Michelle S; Minhas, Paras S; Mendiola, Justin H; Midttun, Øivind; Ulvik, Arve; Shahid-Besanti, Marian; Linortner, Patricia; Mhatre, Siddhita D; Wang, Qian; Channappa, Divya; Corso, Nicole K; Tian, Lu; Fredericks, Carolyn A; Kerchner, Geoffrey A; Plowey, Edward D; Cholerton, Brenna; Ueland, Per M; Zabetian, Cyrus P; Gray, Nora E; Quinn, Joseph F; Montine, Thomas J; Sha, Sharon J; Longo, Frank M; Wolk, David A; Chen-Plotkin, Alice; Henderson, Victor W; Wyss-Coray, Tony; Wagner, Anthony D; Mormino, Elizabeth C; Aghaeepour, Nima; Poston, Kathleen L; Andreasson, Katrin I

Parkinson's disease is characterized by vitamin B6-dependent inflammatory kynurenine pathway dysfunction Journal Article

In: NPJ Parkinsons Dis, vol. 11, no. 1, pp. 96, 2025, ISSN: 2373-8057.

Abstract | Links | BibTeX

13.

Ramos-Rodríguez, Carla; Rojas-Gomez, Alejandra; Santos-Calderón, Luis A; Ceruelo, Santiago; Ríos, Lídia; Ueland, Per M; Fernandez-Ballart, Joan D; Salas-Huetos, Albert; Murphy, Michelle M

The l-Arginine pathway may act as a mediator in the association between impaired one-carbon metabolism and hypertension Journal Article

In: Biochimie, vol. 230, pp. 86–94, 2025, ISSN: 1638-6183.

Abstract | Links | BibTeX

14.

Svenningsson, Mads M; Svingen, Gard Ft; Ueland, Per M; Sulo, Gerhard; Bjørnestad, Espen Ø; Pedersen, Eva R; Dhar, Indu; Nilsen, Dennis W; Nygård, Ottar

Elevated plasma trimethyllysine is associated with incident atrial fibrillation Journal Article

In: Am J Prev Cardiol, vol. 21, pp. 100932, 2025, ISSN: 2666-6677.

Abstract | Links | BibTeX

15.

Damerell, Victoria; Klaassen-Dekker, Niels; Brezina, Stefanie; Ose, Jennifer; Ulvik, Arve; van Roekel, Eline H; Holowatyj, Andreana N; Baierl, Andreas; Böhm, Jürgen; Bours, Martijn J L; Brenner, Hermann; de Wilt, Johannes H W; Grady, William M; Habermann, Nina; Hoffmeister, Michael; Keski-Rahkonen, Pekka; Lin, Tengda; Schirmacher, Peter; Schrotz-King, Petra; Ulrich, Alexis B; van Duijnhoven, Fränzel J B; Warby, Christy A; Shibata, David; Toriola, Adetunji T; Figueiredo, Jane C; Siegel, Erin M; Li, Christopher I; Gsur, Andrea; Kampman, Ellen; Schneider, Martin; Ueland, Per M; Weijenberg, Matty P; Ulrich, Cornelia M; Kok, Dieuwertje E; and, Biljana Gigic

Circulating tryptophan-kynurenine pathway metabolites are associated with all-cause mortality among patients with stage I-III colorectal cancer Journal Article

In: Int J Cancer, vol. 156, no. 3, pp. 552–565, 2025, ISSN: 1097-0215.

Abstract | Links | BibTeX

16.

Fossdal, Guri; Braadland, Peder; Hov, Johannes Roksund; Husebye, Eystein Sverre; Folseraas, Trine; Ueland, Per Magne; Ulvik, Arve; Karlsen, Tom Hemming; Berge, Rolf Kristian; Vesterhus, Mette

Mitochondrial dysfunction and lipid alterations in primary sclerosing cholangitis Journal Article

In: Scand J Gastroenterol, vol. 60, no. 2, pp. 165–173, 2025, ISSN: 1502-7708.

Abstract | Links | BibTeX

17.

Walzik, David; Joisten, Niklas; Schenk, Alexander; Trebing, Sina; Schaaf, Kirill; Metcalfe, Alan J; Spiliopoulou, Polyxeni; Hiefner, Johanna; McCann, Adrian; Watzl, Carsten; Ueland, Per Magne; Gehlert, Sebastian; Worthmann, Anna; Brenner, Charles; Zimmer, Philipp

Acute exercise boosts NAD metabolism of human peripheral blood mononuclear cells Journal Article

In: Brain Behav Immun, vol. 123, pp. 1011–1023, 2025, ISSN: 1090-2139.

Abstract | Links | BibTeX

18.

Santos-Calderón, Luis A; Cavallé-Busquets, Pere; Ramos-Rodríguez, Carla; Grifoll, Carme; Rojas-Gómez, Alejandra; Ballesteros, Mónica; Ueland, Per M; Murphy, Michelle M

Folate and cobalamin status, indicators, modulators, interactions, and reference ranges from early pregnancy until birth: the Reus-Tarragona birth cohort study Journal Article

In: Am J Clin Nutr, vol. 120, no. 5, pp. 1269–1283, 2024, ISSN: 1938-3207.

Abstract | Links | BibTeX

19.

Anfinsen, Åslaug Matre; Myklebust, Vilde Haugen; Johannesen, Christina Osland; Christensen, Jacob Juel; Laupsa-Borge, Johnny; Dierkes, Jutta; Nygård, Ottar; McCann, Adrian; Rosendahl-Riise, Hanne; Lysne, Vegard

Serum concentrations of lipids, ketones and acylcarnitines during the postprandial and fasting state: the Postprandial Metabolism (PoMet) study in healthy young adults Journal Article

In: Br J Nutr, vol. 132, no. 7, pp. 851–861, 2024, ISSN: 1475-2662.

Abstract | Links | BibTeX

20.

Holthuijsen, Daniëlle D B; van Roekel, Eline H; Bours, Martijn J L; Ueland, Per M; Breukink, Stéphanie O; Janssen-Heijnen, Maryska L G; Keulen, Eric T P; Brezina, Stefanie; Gigic, Biljana; Peoples, Anita R; Ulrich, Cornelia M; Ulvik, Arve; Weijenberg, Matty P; Eussen, Simone J P M

Longitudinal associations of plasma kynurenines and ratios with fatigue and quality of life in colorectal cancer survivors up to 12 months post-treatment Journal Article

In: Int J Cancer, vol. 155, no. 7, pp. 1172–1190, 2024, ISSN: 1097-0215.

Abstract | Links | BibTeX

562 entries « 1 of 29 »

Olink Proteomics

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Customized analyses

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Mix-and-Match

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Ready-to-Run

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