Bevital AS

Stability curves

This page provides data on the stability during storage and freezing/thawing of most biomarkers or metabolites included in the repertoire of BEVITAL by April 2019.
The panels (example on the right; click on biomarkers below) show the stability of all biomarkers in EDTA plasma and serum at room temperature (left) for the indicated duration and after increasing number of freeze-thaw cycles (right). The white zone indicates +/- 15% deviation from the average of the first three time points for plasma. Data are given as geometric mean with standard error (SE) for samples from 15 healthy subjects. For some pairs of metabolite (asparagine / aspartic acid, glutamine / glutamic acid, thiamine monophosphate (TMP) / thiamine, flavin mononucleotide (FMN) / riboflavin, 5-methyl-tetrahydrofolate / 4-alfa-hydroxy-5-methyl-THF) characterized by interconversion, the lower panel shows the concentration of the two metabolites combined. Thus, summarizing the concentrations of such source-product pairs is a useful strategy to correct for preanalytical instability

E: LC-MS/MS

Folate species and catabolites.

F: Microbiological assay

Folate (B9) and cobalamin (B12).

H: LC-MS/MS

Lipid-soluble vitamins and long-chain acylcarnitines.
Folate species and catabolites.
Folate (B9) and cobalamin (B12).
Lipid-soluble vitamins and long-chain acylcarnitines.
May 25, 2022

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