Targeted Metabolomics Services


Updated 21/12/2022

What is measured?

Synonyms: 3-Aminopropanoic acid, 3-aminopropionic acid.
Method(s): GC-MS/MS (1).

What is β-Alanine?

β-Alanine (bAla) is a naturally occurring beta-amino acid that is formed during degradation of carnosine and anserine, but also serves as a precursor for the synthesis of these histidine-containing dipeptides. This explains why beta-alanine may reflect the amount of carnosine/anserine in the body, and serves as a biomarker for the consumption of meat, especially red meat.
β-Alanine is used as a supplement. High levels, as encountered in some inborn errors of metabolism causing hyper-beta-alaninemia, may act as a neurotoxin and as a mitochondrial toxin. Circulating levels is inversely associated with dementia (2).


To investigate the metabolomic signature of human diseases.

Specimen, collection and processing

Patient/subject: No special precaution.
Matrix: Serum or EDTA plasma.
Volume: Minimum volume is 50 µL, but 200 µL is optimal and allows reanalysis.
Preparation and stability: Probably stable.


Frozen, on dry ice. (for general instruction on transportation, click here)

Reported values, interpretation

Reported values: 0.5-10 µmol/L
Intraclass correlation coefficient (ICC): na.


1. Midttun, Ø., McCann, A., Aarseth, O., Krokeide, M., Kvalheim, G., Meyer, K., and Ueland, P.M. (2016). Combined measurement of 6 fat-soluble vitamins and 26 water-soluble functional vitamin markers and amino acids in 50 μL of serum or plasma by high-throughput mass spectrometry. Anal Chem 88, 10427-436.
2. Hata, J., Ohara, T., Katakura, Y., Shimizu, K., Yamashita, S., Yoshida, D., Honda, T., Hirakawa, Y., Shibata, M., Sakata, S., Kitazono, T., Kuhara, S., & Ninomiya, T. (2019). Association Between Serum β-Alanine and Risk of Dementia. Am J Epidemiol, 188, 1637-164.

This website uses cookies. By continuing to use this site, you accept our use of cookies.  Learn more

Scroll to Top

Join our Mailing list!

Get updates of our latest articles, events and method developments.