Publications
BEVITAL is partner in numerous projects and reseach collaborations, and publications range from instrument development, establishment of new technologies, to application in large epidemiological projects.
Publications 2016-2023
2023
1. Anfinsen, A. M., Johannesen, C. O., Myklebust, V. H., Rosendahl-Riise, H., McCann, A., Nygard, O. K., et al. (2023). Time-resolved concentrations of serum amino acids, one-carbon metabolites and B-vitamin biomarkers during the postprandial and fasting state: the Postprandial Metabolism in Healthy Young Adults (PoMet) Study. Br J Nutr, 1-15.
2. Anfinsen, A. M., Rosendahl-Riise, H., Nygard, O., Tell, G. S., Ueland, P. M., Ulvik, A., et al. (2023). Exploratory analyses on the effect of time since last meal on concentrations of amino acids, lipids, one-carbon metabolites, and vitamins in the Hordaland Health Study. Eur J Nutr, 62(7), 3079-3095.
3. Bager, P., Hvas, C. L., Hansen, M. M., Ueland, P., & Dahlerup, J. F. (2023). B-vitamins, related vitamers, and metabolites in patients with quiescent inflammatory bowel disease and chronic fatigue treated with high dose oral thiamine. Mol Med, 29(1), 143.
4. Bakker, L., Kohler, S., Eussen, S., Choe, K., van den Hove, D. L. A., Kenis, G., et al. (2023). Correlations between kynurenines in plasma and CSF, and their relation to markers of Alzheimer’s disease pathology. Brain Behav Immun, 111, 312-319.
5. Bakker, L., Ramakers, I., S, J. P. M. E., Choe, K., van den Hove, D. L. A., Kenis, G., et al. (2023). The role of the kynurenine pathway in cognitive functioning after stroke: A prospective clinical study. J Neurol Sci, 454, 120819.
6. Bjorke-Monsen, A. L., Varsi, K., Sakkestad, S. T., Ulvik, A., Ebbing, C., & Ueland, P. M. (2023). Lower levels of the neuroprotective tryptophan metabolite, kynurenic acid, in users of estrogen contraceptives. Sci Rep, 13(1), 16370.
7. Bjorke-Monsen, A. L., Varsi, K., Sakkestad, S. T., Ulvik, A., & Ueland, P. M. (2023). Assessment of vitamin B6 status in never-pregnant, pregnant and postpartum women and their infants. Eur J Nutr, 62(2), 867-878.
8. Bjorke-Monsen, A. L., Varsi, K., Ulvik, A., Sakkestad, S. T., & Ueland, P. M. (2023). A Vegetarian Diet Significantly Changes Plasma Kynurenine Concentrations. Biomolecules, 13(2).
9. Bjune, M. S., Lawrence-Archer, L., Laupsa-Borge, J., Sommersten, C. H., McCann, A., Glastad, R. C., et al. (2023). Metabolic role of the hepatic valine/3-hydroxyisobutyrate (3-HIB) pathway in fatty liver disease. EBioMedicine, 91, 104569.
10. Braadland, P. R., Bergquist, A., Kummen, M., Bossen, L., Engesaeter, L. K., Reims, H. M., et al. (2023). Clinical and biochemical impact of vitamin B6 deficiency in primary sclerosing cholangitis before and after liver transplantation. J Hepatol, 79(4), 955-966.
11. Chandyo, R. K., Kvestad, I., Ulak, M., Ranjitkar, S., Hysing, M., Shrestha, M., et al. (2023). The effect of vitamin B12 supplementation during pregnancy on infant growth and development in Nepal: a community-based, double-blind, randomised, placebo-controlled trial. Lancet, 401(10387), 1508-1517.
12. Dahl, H., Meyer, K., Sandnes, K., Welland, N. L., Arnesen, I., Marti, H. P., et al. (2023). Cystatin C proteoforms in chronic kidney disease. PLoS One, 18(2), e0269436.
13. Dhar, I., Lysne, V., Ulvik, A., Svingen, G. F. T., Pedersen, E. R., Bjornestad, E. O., et al. (2023). Plasma methylmalonic acid predicts risk of acute myocardial infarction and mortality in patients with coronary heart disease: A prospective 2-cohort study. J Intern Med, 293(4), 508-519.
14. Dhar, I., Svingen, G. F., Bjornestad, E. O., Ulvik, A., Saeed, S., & Nygard, O. K. (2023). B-vitamin Treatment Modifies the Mortality Risk Associated with Calcium Channel Blockers in Patients with Suspected Stable Angina Pectoris: A Prospective Cohort Study. Am J Clin Nutr, 118(1), 77-84.
15. Dierkes, J., Dietrich, S., Abraham, K., Monien, B. H., McCann, A., Borga, K., et al. (2023). Stable isotope ratios of nitrogen and carbon as biomarkers of a vegan diet. Eur J Nutr, 62(1), 433-441.
16. Giil, L. M., Hanseth, S., Bojovic, O., Nordrehaug, J. E., Ueland, P. M., Meyer, K., et al. (2023). The inverse association between the apolipoprotein E epsilon4 allele and C-reactive protein levels is stronger in persons with obesity and diabetes. Scand J Immunol, e13323.
17. Hagen, I. V., Helland, A., Bratlie, M., Midttun, O., McCann, A., Ulvik, A., et al. (2023). Serum concentrations of amino acids and tryptophan metabolites are affected by consumption of a light breakfast: a clinical intervention study in adults with overweight or obesity. BMC Nutr, 9(1), 10.
18. Hesselink, A., Winkvist, A., Lindahl, B., Ueland, P. M., Schneede, J., Johansson, I., et al. (2023). Healthy Nordic diet and associations with plasma concentrations of metabolites in the choline oxidation pathway: a cross-sectional study from Northern Sweden. Nutr J, 22(1), 26.
19. Holthuijsen, D. D. B., van Roekel, E. H., Bours, M. J. L., Ueland, P. M., Breukink, S. O., Janssen-Heijnen, M. L. G., et al. (2023). Longitudinal associations of macronutrient and micronutrient intake with plasma kynurenines in colorectal cancer survivors up to 12 months posttreatment. Am J Clin Nutr, 118(5), 865-880.
20. Jersin, R. A., Sri Priyanka Tallapragada, D., Skartveit, L., Bjune, M. S., Muniandy, M., Lee-Odegard, S., et al. (2023). Impaired Adipocyte SLC7A10 Promotes Lipid Storage in Association With Insulin Resistance and Altered BCAA Metabolism. J Clin Endocrinol Metab, 108(9), 2217-2229.
21. Knapskog, A. B., Aksnes, M., Edwin, T. H., Ueland, P. M., Ulvik, A., Fang, E. F., et al. (2023). Higher concentrations of kynurenic acid in CSF are associated with the slower clinical progression of Alzheimer’s disease. Alzheimers Dement.
22. Kringeland, E., Gerdts, E., Ulvik, A., Tell, G. S., Igland, J., Haugsgjerd, T. R., et al. (2023). Inflammation, sex, blood pressure changes and hypertension in midlife: the Hordaland Health Study. J Hum Hypertens, 37(8), 718-725.
23. Kupjetz, M., Patt, N., Joisten, N., Ueland, P. M., McCann, A., Gonzenbach, R., et al. (2023). The serum kynurenine pathway metabolic profile is associated with overweight and obesity in multiple sclerosis. Mult Scler Relat Disord, 72, 104592.
24. Michels, K. A., Weinstein, S. J., Albert, P. S., Black, A., Brotzman, M., Diaz-Mayoral, N. A., et al. (2023). The Influence of Preanalytical Biospecimen Handling on the Measurement of B Vitamers, Amino Acids, and Other Metabolites in Blood. Biopreserv Biobank, 21(5), 467-476.
25. Midttun, O., Ulvik, A., Meyer, K., Zahed, H., Giles, G. G., Manjer, J., et al. (2023). A cross-sectional study of inflammatory markers as determinants of circulating kynurenines in the Lung Cancer Cohort Consortium. Sci Rep, 13(1), 1011.
26. Monasso, G. S., Hoang, T. T., Mancano, G., Fernandez-Barres, S., Dou, J., Jaddoe, V. W. V., et al. (2023). A meta-analysis of epigenome-wide association studies on pregnancy vitamin B12 concentrations and offspring DNA methylation. Epigenetics, 18(1), 2202835.
27. Nikiema, V., Kangas, S. T., Salpeteur, C., Briend, A., Talley, L., Friis, H., et al. (2023). Vitamin B12 Status before and after Outpatient Treatment of Severe Acute Malnutrition in Children Aged 6-59 Months: A Sub-Study of a Randomized Controlled Trial in Burkina Faso. Nutrients, 15(16).
28. O’Keeffe, M., Oterhals, A., Weishaupt, H., Leh, S., Ulvik, A., Ueland, P. M., et al. (2023). A diet containing cod backbone proteins attenuated the development of mesangial sclerosis and tubular dysfunction in male obese BTBR ob/ob mice. Eur J Nutr, 62(8), 3227-3240.
29. Ose, J., Gigic, B., Brezina, S., Lin, T., Peoples, A. R., Schobert, P. P., et al. (2023). Higher Plasma Creatinine Is Associated with an Increased Risk of Death in Patients with Non-Metastatic Rectal but Not Colon Cancer: Results from an International Cohort Consortium. Cancers (Basel), 15(13).
30. Paragomi, P., Wang, R., Huang, J. Y., Midttun, O., Ulvik, A., Ueland, P. M., et al. (2023). The Association Between Serum Riboflavin and Flavin Mononucleotide With Pancreatic Cancer: Findings From a Prospective Cohort Study. Pancreas, 52(2), e127-e134.
31. Rojas-Gomez, A., Sole-Navais, P., Cavalle-Busquets, P., Ornosa-Martin, G., Grifoll, C., Ramos-Rodriguez, C., et al. (2023). Pregnancy homocysteine and cobalamin status predict childhood metabolic health in the offspring. Pediatr Res, 93(3), 633-642.
32. , S.M.G., Konijnenberg, C., Kvestad, I., McCann, A., Ueland, P. M., Naess Sleire, S., et al. (2023). Vitamin B12 and Folate Status in Pregnant Females and Their Infants in Norway: Secondary Analysis from the Mommy’s Food Study. J Nutr.
33. Sommersten, C. H., Gjerde, E. S., Laupsa-Borge, J., Andersen, A. I., Lawrence-Archer, L., McCann, A., et al. (2023). Relationship between Ketones, Ghrelin, and, Appetite on Isocaloric Diets with Varying Carbohydrate Quality and Amount: Results from a Randomized Controlled Trial in People with Obesity (CARBFUNC). J Nutr, 153(2), 459-469.
34. Titlestad, I., Watne, L. O., Caplan, G. A., McCann, A., Ueland, P. M., Neerland, B. E., et al. (2023). Impaired glucose utilization in the brain of patients with delirium following hip fracture. Brain.
35. Ueland, H. O., Ulvik, A., Lovas, K., Wolff, A. S. B., Breivik, L. E., Stokland, A. M., et al. (2023). Systemic Activation of the Kynurenine Pathway in Graves Disease With and Without Ophthalmopathy. J Clin Endocrinol Metab, 108(6), 1290-1297.
36. Ulak, M., Kvestad, I., Chandyo, R. K., Schwinger, C., Basnet, S., Shrestha, M., et al. (2023). The Effect of Vitamin B(12) Supplementation on Leukocyte Telomere Length in Mildly Stunted Nepalese Children: A Secondary Outcome of a Randomized Controlled Trial. J Nutr.
37. Watne, L. O., Pollmann, C. T., Neerland, B. E., Quist-Paulsen, E., Halaas, N. B., Idland, A. V., et al. (2023). Cerebrospinal fluid quinolinic acid is strongly associated with delirium and mortality in hip-fracture patients. J Clin Invest, 133(2).
2022
1. Bjørnestad, E., Dhar, I., Svingen, G., Pedersen, E., Svenningsson, M., Tell, G., et al. (2021). Trimethyllysine predicts all-cause and cardiovascular mortality in community-dwelling adults and patients with coronary heart disease. Eur Heart J Open, 1(1), oeab007.
2. Bjørke-Monsen, A., Varsi, K., Sakkestad, S., Ulvik, A., & Ueland, P. (2022). Assessment of vitamin B6 status in never-pregnant, pregnant and postpartum women and their infants. Eur J Nutr.
3. Bjørnestad, E., Dhar, I., Svingen, G., Pedersen, E., Ørn, S., Svenningsson, M., et al. (2022). Circulating trimethylamine N-oxide levels do not predict 10-year survival in patients with or without coronary heart disease. J Intern Med, 292(6), 915-924.
4. Clasen, J., Heath, A., Van Puyvelde, H., Huybrechts, I., Park, J., Ferrari, P., et al. (2022). Biomarkers of the transsulfuration pathway and risk of renal cell carcinoma in the European Prospective Investigation into Cancer and Nutrition (EPIC) study. Int J Cancer, 151(5), 708-716.
5. Clements, M., Heffernan, M., Ward, M., Hoey, L., Doherty, L., Hack Mendes, R., et al. (2022). A 2-Year Randomized Controlled Trial With Low-Dose B-Vitamin Supplementation Shows Benefits on Bone Mineral Density in Adults With Lower B12 Status. J Bone Miner Res, 37(12), 2443-2455.
6. Gao, J., McCann, A., Laupsa-Borge, J., Nygård, O., Ueland, P., & Meyer, K. (2022). Within-person reproducibility of proteoforms related to inflammation and renal dysfunction. Sci Rep, 12(1), 7426.
7. Gigic, B., van Roekel, E., Holowatyj, A., Brezina, S., Geijsen, A., Ulvik, A., et al. (2022). Cohort profile: Biomarkers related to folate-dependent one-carbon metabolism in colorectal cancer recurrence and survival – the FOCUS Consortium. BMJ Open, 12(12), e062930.
8. Helland, A., Bratlie, M., Hagen, I., Midttun, Ø., Ulvik, A., Mellgren, G., et al. (2022). Consumption of a light meal affects serum concentrations of one-carbon metabolites and B-vitamins. A clinical intervention study. Br J Nutr, 1-10.
9. Holowatyj, A., Ose, J., Gigic, B., Lin, T., Ulvik, A., Geijsen, A., et al. (2022). Higher vitamin B6 status is associated with improved survival among patients with stage I-III colorectal cancer. Am J Clin Nutr, 116(2), 303-313.
10. Holthuijsen, D., Bours, M., Roekel, E., Breukink, S., Janssen-Heijnen, M., Keulen, E., et al. (2022). Longitudinal Associations of Adherence to the Dietary World Cancer Research Fund/American Institute for Cancer Research (WCRF/AICR) and Dutch Healthy Diet (DHD) Recommendations with Plasma Kynurenines in Colorectal Cancer Survivors after Treatment. Nutrients, 14(23).
11. Husebye, E., Wendel, A., Gilhus, N., Riedel, B., & Bjørk, M. (2022). Plasma unmetabolized folic acid in pregnancy and risk of autistic traits and language impairment in antiseizure medication-exposed children of women with epilepsy. Am J Clin Nutr, 115(5), 1432-1440.
12. Kringeland, E., Gerdts, E., Ulvik, A., Tell, G., Igland, J., Haugsgjerd, T., et al. (2022). Inflammation, sex, blood pressure changes and hypertension in midlife: the Hordaland Health Study. J Hum Hypertens.
13. Luu, H., Paragomi, P., Wang, R., Huang, J., Adams-Haduch, J., Midttun, Ø., et al. (2022). The Association between Serum Serine and Glycine and Related-Metabolites with Pancreatic Cancer in a Prospective Cohort Study. Cancers (Basel), 14(9), 2199.
14. Midtbø, H., Kringeland, E., Gerdts, E., Ueland, P., Meyer, K., Linde, A., et al. (2022). Biomarkers of inflammation and left ventricular remodelling in psoriasis patients treated with infliximab. Int J Immunopathol Pharmacol, 36, 1.
15. Querido, N., Kenkhuis, M., van Roekel, E., Breukink, S., van Duijnhoven, F., Janssen-Heijnen, M., et al. (2022). Longitudinal Associations between Inflammatory Markers and Fatigue up to Two Years after Colorectal Cancer Treatment. Cancer Epidemiol Biomarkers Prev, 31(8), 1638-1649.
16. Rojas-Gómez, A., Solé-Navais, P., Cavallé-Busquets, P., Ornosa-Martin, G., Grifoll, C., Ramos-Rodriguez, C., et al. (2022). Pregnancy homocysteine and cobalamin status predict childhood metabolic health in the offspring. Pediatr Res.
17. Solvang, S., Hodge, A., Watne, L., Cabral-Marques, O., Nordrehaug, J., Giles, G., et al. (2022). Kynurenine Pathway Metabolites in the Blood and Cerebrospinal Fluid Are Associated with Human Aging. Oxid Med Cell Longev, 2022, 5019752.
18. Ta, L., Chan, J., Yap, G., Huang, C., Tham, E., Loo, E., et al. (2022). Prenatal diet, plasma micronutrients/metabolome and inflammatory status influence the development of atopic eczema in early childhood. Allergy.
19. Tan, K., Tint, M., Kothandaraman, N., Michael, N., Sadananthan, S., Velan, S., et al. (2022). The Kynurenine Pathway Metabolites in Cord Blood Positively Correlate With Early Childhood Adiposity. J Clin Endocrinol Metab, 107(6), e2464-e2473.
20. Tan, K., Tint, M., Kothandaraman, N., Yap, F., Godfrey, K., Lee, Y., et al. (2022). Association of plasma kynurenine pathway metabolite concentrations with metabolic health risk in prepubertal Asian children. Int J Obes (Lond), 46(6), 1128-1137.
21. Ulak, M., Kvestad, I., Chandyo, R., Ranjitkar, S., Hysing, M., Schwinger, C., et al. (2022). The effect of infant vitamin B12 supplementation on neurodevelopment: A follow-up of a randomized placebo-controlled trial in Nepal. Br J Nutr, 1-18.
2021
1. Davydova, E., Shimazu, T., Schuhmacher, M. K., Jakobsson, M. E., Willemen, H. L. D. M., Liu, T. et al. (2021). The methyltransferase METTL9 mediates pervasive 1-methylhistidine modification in mammalian proteomes. Nat Commun, 12(1), 891.
2. Bjune, M. S., Lindquist, C., Hallvardsdotter Stafsnes, M., Bjørndal, B., Bruheim, P., Aloysius, T. A. et al. (2021). Plasma 3-hydroxyisobutyrate (3-HIB) and methylmalonic acid (MMA) are markers of hepatic mitochondrial fatty acid oxidation in male Wistar rats. Biochim Biophys Acta Mol Cell Biol Lipids, 1866(4), 158887. Baumgartner, R., Berg, M., Matic, L., Polyzos, K. P., Forteza, M. J., Hjorth, S. A. et al. (2021). Evidence that a deviation in the kynurenine pathway aggravates atherosclerotic disease in humans. J Intern Med, 289(1), 53-68.
3. Pan, X. F., Yang, J. J., Shu, X. O., Moore, S. C., Palmer, N. D., Guasch-Ferré, M. et al. (2021). Associations of circulating choline and its related metabolites with cardiometabolic biomarkers: an international pooled analysis. Am J Clin Nutr, 114(3), 893-906.
4. Groven, N., Reitan, S. K., Fors, E. A., & Guzey, I. C. (2021). Kynurenine metabolites and ratios differ between Chronic Fatigue Syndrome, Fibromyalgia, and healthy controls. Psychoneuroendocrinology, 131, 105287.
5. Lau, H. X., El-Heis, S., Yap, Q. V., Chan, Y. H., Tan, C. P. T., Karnani, N. et al. (2021). Role of maternal tryptophan metabolism in allergic diseases in the offspring. Clin Exp Allergy, 51(10), 1346-1360.
6. Wesnes, K., Myhr, K. M., Riise, T., Kvistad, S. S., Torkildsen, Ø., Wergeland, S. et al. (2021). Low vitamin D, but not tobacco use or high BMI, is associated with long-term disability progression in multiple sclerosis. Mult Scler Relat Disord, 50, 102801.
7. Drobnic, F., Storsve, A. B., Burri, L., Ding, Y., Banquells, M., Riera, J. et al. (2021). Krill-Oil-Dependent Increases in HS-Omega-3 Index, Plasma Choline and Antioxidant Capacity in Well-Conditioned Power Training Athletes. Nutrients, 13(12).
8. Alme, K. N., Ulvik, A., Askim, T., Assmus, J., Mollnes, T. E., Naik, M. et al. (2021). Neopterin and kynurenic acid as predictors of stroke recurrence and mortality: a multicentre prospective cohort study on biomarkers of inflammation measured three months after ischemic stroke. BMC Neurol, 21(1), 476.
9. Samanic, C. M., Yue, Y., Cote, D. J., Stampfer, M. J., Wang, M., McCann, A. et al. (2022). A prospective study of pre-diagnostic circulating tryptophan and kynurenine, and the kynurenine/tryptophan ratio and risk of glioma. Cancer Epidemiol, 76, 102075.
10. Söderström, E., Nilsson, T. K., Schneede, J., Ueland, P. M., Midttun, Ø., Gylling, B. et al. (2021). Plasma Cotinine Is Positively Associated with Homocysteine in Smokers but Not in Users of Smokeless Tobacco. Int J Environ Res Public Health, 18(21).
11. Wu, X., Ueland, P. M., Roper, J., Koh, G. Y., Liang, X., Crott, J. W. et al. (2021). Combined Supplementation with Vitamin B-6 and Curcumin is Superior to Either Agent Alone in Suppressing Obesity-Promoted Colorectal Tumorigenesis in Mice. J Nutr, 151(12), 3678-3688.
12. Schwinger, C., Sharma, S., Chandyo, R. K., Hysing, M., Kvestad, I., Ulak, M. et al. (2021). Cobalamin and folate status in women during early pregnancy in Bhaktapur, Nepal. J Nutr Sci, 10, e57.
13. Bakker, L., Ramakers, I. H. G. B., van Boxtel, M. P. J., Schram, M. T., Stehouwer, C. D. A., van der Kallen, C. J. H. et al. (2021). Associations between plasma kynurenines and cognitive function in individuals with normal glucose metabolism, prediabetes and type 2 diabetes: the Maastricht Study. Diabetologia, 64(11), 2445-2457.
14. Alme, K. N., Askim, T., Assmus, J., Mollnes, T. E., Naik, M., Næss, H. et al. (2021). Investigating novel biomarkers of immune activation and modulation in the context of sedentary behaviour: a multicentre prospective ischemic stroke cohort study. BMC Neurol, 21(1), 318.
15. Li, S. X., Hodge, A. M., MacInnis, R. J., Bassett, J. K., Ueland, P. M., Midttun, Ø. et al. (2021). Inflammation-Related Marker Profiling of Dietary Patterns and All-cause Mortality in the Melbourne Collaborative Cohort Study. J Nutr, 151(10), 2908-2916.
16. Vikøren, L. A., Drotningsvik, A., Midttun, Ø., McCann, A., Bergseth, M. T., Austgulen, M. H. et al. (2021). Baked cod consumption delayed the development of kidney and liver dysfunction and affected plasma amino acid concentrations, but did not affect blood pressure, blood glucose or liver triacylglycerol concentrations in obese fa/fa Zucker rats. Nutr Res, 92, 72-83.
17. Zahed, H., Johansson, M., Ueland, P. M., Midttun, Ø., Milne, R. L., Giles, G. G. et al. (2021). Epidemiology of 40 blood biomarkers of one-carbon metabolism, vitamin status, inflammation, and renal and endothelial function among cancer-free older adults. Sci Rep, 11(1), 13805.
18. Papadimitriou, N., Gunter, M. J., Murphy, N., Gicquiau, A., Achaintre, D., Brezina, S. et al. (2021). Circulating tryptophan metabolites and risk of colon cancer: Results from case-control and prospective cohort studies. Int J Cancer, 149(9), 1659-1669.
19. Ulvik, A., McCann, A., Midttun, Ø., Meyer, K., Godfrey, K. M., & Ueland, P. M. (2021). Quantifying Precision Loss in Targeted Metabolomics Based on Mass Spectrometry and Nonmatching Internal Standards. Anal Chem, 93(21), 7616-7624.
20. Solvik, B. S., Øyen, J., Kvestad, I., Markhus, M. W., Ueland, P. M., McCann, A. et al. (2021). Biomarkers and Fatty Fish Intake: A Randomized Controlled Trial in Norwegian Preschool Children. J Nutr, 151(8), 2134-2141.
21. Yue, Y., Creed, J. H., Cote, D. J., Stampfer, M. J., Wang, M., Midttun, Ø. et al. (2021). Pre-diagnostic circulating concentrations of fat-soluble vitamins and risk of glioma in three cohort studies. Sci Rep, 11(1), 9318.
22. McCann, A., Aarsland, D., Ueland, P. M., Solvang, S. H., Nordrehaug, J. E., & Giil, L. M. (2021). Serum tyrosine is associated with better cognition in Lewy body dementia. Brain Res, 1765, 147481.
23. Clasen, J. L., Heath, A. K., Van Puyvelde, H., Huybrechts, I., Park, J. Y., Ferrari, P. et al. (2021). A comparison of complementary measures of vitamin B6 status, function, and metabolism in the European Prospective Investigation into Cancer and Nutrition (EPIC) study. Am J Clin Nutr, 114(1), 338-347.
24. Aubi, O., Prestegård, K. S., Jung-Kc, K., Shi, T. S., Ying, M., Grindheim, A. K. et al. (2021). The Pah-R261Q mouse reveals oxidative stress associated with amyloid-like hepatic aggregation of mutant phenylalanine hydroxylase. Nat Commun, 12(1), 2073.
25. Munger, R. G., Kuppuswamy, R., Murthy, J., Balakrishnan, K., Thangavel, G., Sambandam, S. et al. (2021). Maternal Vitamin B(12) Status and Risk of Cleft Lip and Cleft Palate Birth Defects in Tamil Nadu State, India. Cleft Palate Craniofac J, 58(5), 567-576.
26. Tillmann, S., Awwad, H. M., MacPherson, C. W., Happ, D. F., Treccani, G., Geisel, J. et al. (2021). The Kynurenine Pathway Is Upregulated by Methyl-deficient Diet and Changes Are Averted by Probiotics. Mol Nutr Food Res, 65(9), e2100078.
27. Menzel, J., Abraham, K., Stangl, G. I., Ueland, P. M., Obeid, R., Schulze, M. B. et al. (2021). Vegan Diet and Bone Health-Results from the Cross-Sectional RBVD Study. Nutrients, 13(2).
28. Gumpenberger, T., Brezina, S., Keski-Rahkonen, P., Baierl, A., Robinot, N., Leeb, G. et al. (2021). Untargeted Metabolomics Reveals Major Differences in the Plasma Metabolome between Colorectal Cancer and Colorectal Adenomas. Metabolites, 11(2).
29. Ose, J., Gigic, B., Brezina, S., Lin, T., Baierl, A., Geijsen, A. J. M. R. et al. (2021). Targeted Plasma Metabolic Profiles and Risk of Recurrence in Stage II and III Colorectal Cancer Patients: Results from an International Cohort Consortium. Metabolites, 11(3).
30. Koole, J. L., Bours, M. J. L., Geijsen, A. J. M. R., Gigic, B., Ulvik, A., Kok, D. E. et al. (2021). Circulating B-vitamin biomarkers and B-vitamin supplement use in relation to quality of life in patients with colorectal cancer: results from the FOCUS consortium. Am J Clin Nutr, 113(6), 1468-1481.
31. Drivsholm, N., Knudsen, A. D., Faurholt-Jepsen, M., Midttun, Ø., Trøseid, M., Kirkegaard-Klitbo, D. M. et al. (2021). Alterations in the Kynurenine Pathway of Tryptophan Metabolism Are Associated With Depression in People Living With HIV. J Acquir Immune Defic Syndr, 87(2), e177-e181.
32. Dhillon, A. K., Rupp, C., Bergquist, A., Voitl, R., Folseraas, T., Trøseid, M. et al. (2021). Associations of neopterin and kynurenine-tryptophan ratio with survival in primary sclerosing cholangitis. Scand J Gastroenterol, 56(4), 443-452.
33. Helland, A., Bratlie, M., Hagen, I. V., Midttun, Ø., Sveier, H., Mellgren, G. et al. (2021). Effect of high intake of cod or salmon on serum total neopterin concentration: a randomised clinical trial. Eur J Nutr, 60(6), 3237-3248.
34. Kvestad, I., McCann, A., Chandyo, R. K., Giil, L. M., Shrestha, M., Ulak, M. et al. (2021). One-Carbon Metabolism in Nepalese Infant-Mother Pairs and Child Cognition at 5 Years Old. J Nutr, 151(4), 883-891.
35. Jersin, R. Å., Tallapragada, D. S. P., Madsen, A., Skartveit, L., Fjære, E., McCann, A. et al. (2021). Role of the Neutral Amino Acid Transporter SLC7A10 in Adipocyte Lipid Storage, Obesity, and Insulin Resistance. Diabetes, 70(3), 680-695.
36. Kummen, M., Thingholm, L. B., Rühlemann, M. C., Holm, K., Hansen, S. H., Moitinho-Silva, L. et al. (2021). Altered Gut Microbial Metabolism of Essential Nutrients in Primary Sclerosing Cholangitis. Gastroenterology, 160(5), 1784-1798.e0.
37. Gao, J., Ulvik, A., McCann, A., Ueland, P. M., & Meyer, K. (2021). Microheterogeneity and preanalytical stability of protein biomarkers of inflammation and renal function. Talanta, 223(Pt 1), 121774.
38. Bratlie, M., Hagen, I. V., Helland, A., Erchinger, F., Midttun, Ø., Ueland, P. M. et al. (2021). Effects of high intake of cod or salmon on gut microbiota profile, faecal output and serum concentrations of lipids and bile acids in overweight adults: a randomised clinical trial. Eur J Nutr, 60(4), 2231-2248.
39. A novel case of impaired C-reactive protein response following open-heart surgery: A case report and review of the literature. Clin Chim Acta, 520, 196-201.
2020
1. Kummen, M., Thingholm, L. B., Rühlemann, M. C., Holm, K., Hansen, S. H., Moitinho-Silva, L. et al. (2020). Altered gut microbial metabolism of essential nutrients in primary sclerosing cholangitis. Gastroenterology.
2. Gao, J., Ulvik, A., McCann, A., Ueland, P. M., & Meyer, K. (2021). Microheterogeneity and preanalytical stability of protein biomarkers of inflammation and renal function. Talanta, 223(Pt 1), 121774.
3. Strand, T. A., Ulak, M., Hysing, M., Ranjitkar, S., Kvestad, I., Shrestha, M. et al. (2020). Effects of vitamin B12 supplementation on neurodevelopment and growth in Nepalese Infants: A randomized controlled trial. PLoS Med, 17(12), e1003430.
4. Geijsen, A. J. M. R., Ulvik, A., Gigic, B., Kok, D. E., van Duijnhoven, F. J. B., Holowatyj, A. N. et al. (2020). Circulating Folate and Folic Acid Concentrations: Associations With Colorectal Cancer Recurrence and Survival. JNCI Cancer Spectr, 4(5), pkaa051.
5. Lee, S., Gulseth, H. L., Langleite, T. M., Norheim, F., Olsen, T., Refsum, H. et al. (2020). Branched-chain amino acid metabolism, insulin sensitivity and liver fat response to exercise training in sedentary dysglycaemic and normoglycaemic men. Diabetologia.
6. Bratlie, M., Hagen, I. V., Helland, A., Erchinger, F., Midttun, Ø., Ueland, P. M. et al. (2020). Effects of high intake of cod or salmon on gut microbiota profile, faecal output and serum concentrations of lipids and bile acids in overweight adults: a randomised clinical trial. Eur J Nutr.
7. Sardenberg, W. M., Santos, M. C. L. F. S., Skarstein, K., Carvalho Caser, L., Brun, J. G., Ulvik, A. et al. (2020). Acinar adipose tissue infiltration in salivary gland biopsy is associated with kynurenines-Interferon-γ pathway inflammation biomarkers. Clin Exp Rheumatol, 38 Suppl 126(4), 27-33.
8. Schwinger, C., Chowdhury, R., Sharma, S., Bhandari, N., Taneja, S., Ueland, P. M. et al. (2020). Association of Plasma Total Cysteine and Anthropometric Status in 6-30 Months Old Indian Children. Nutrients, 12(10).
9. Arora, N., Strand, T. A., Chandyo, R. K., Elshorbagy, A., Shrestha, L., Ueland, P. M. et al. (2020). Association of Maternal Plasma Total Cysteine and Growth among Infants in Nepal: A Cohort Study. Nutrients, 12(9).
10. Baumgartner, R., Berg, M., Matic, L., Polyzos, K. P., Forteza, M. J., Hjorth, S. A. et al. (2021). Evidence that a deviation in the kynurenine pathway aggravates atherosclerotic disease in humans. J Intern Med, 289(1), 53-68.
11. Holowatyj, A. N., Haffa, M., Lin, T., Scherer, D., Gigic, B., Ose, J. et al. (2020). Multi-omics Analysis Reveals Adipose-tumor Crosstalk in Patients with Colorectal Cancer. Cancer Prev Res (Phila), 13(10), 817-828.
12. Widbom, L., Schneede, J., Midttun, Ø., Ueland, P. M., Karling, P., & Hultdin, J. (2020). Elevated plasma cotinine is associated with an increased risk of developing IBD, especially among users of combusted tobacco. PLoS One, 15(7), e0235536.
13. Nilsen, M. S., Jersin, R. Å., Ulvik, A., Madsen, A., McCann, A., Svensson, P. A. et al. (2020). 3-Hydroxyisobutyrate, A Strong Marker of Insulin Resistance in Type 2 Diabetes and Obesity That Modulates White and Brown Adipocyte Metabolism. Diabetes, 69(9), 1903-1916.
14. Ose, J., Holowatyj, A. N., Nattenmüller, J., Gigic, B., Lin, T., Himbert, C. et al. (2020). Metabolomics profiling of visceral and abdominal subcutaneous adipose tissue in colorectal cancer patients: results from the ColoCare study. Cancer Causes Control, 31(8), 723-735.
15. Vildmyren, I., Halstensen, A., McCann, A., Midttun, Ø., Ueland, P. M., Oterhals, Å. et al. (2020). Effect of Cod Residual Protein Supplementation on Markers of Glucose Regulation in Lean Adults: A Randomized Double-Blind Study. Nutrients, 12(5).
16. Berge, R. K., Cacabelos, D., Señarís, R., Nordrehaug, J. E., Nygård, O., Skorve, J. et al. (2020). Hepatic steatosis induced in C57BL/6 mice by a non-ß oxidizable fatty acid analogue is associated with reduced plasma kynurenine metabolites and a modified hepatic NAD+/NADH ratio. Lipids Health Dis, 19(1), 94.
17. Christine, C. W., Auinger, P., Saleh, N., Tian, M., Bottiglieri, T., Arning, E. et al. (2020). Relationship of Cerebrospinal Fluid Vitamin B12 Status Markers With Parkinson’s Disease Progression. Mov Disord, 35(8), 1466-1471.
18. Svenningsson, M. M., Svingen, G. F. T., Lysne, V., Ueland, P. M., Tell, G. S., Pedersen, E. R. et al. (2020). Transsulfuration metabolites and the association with incident atrial fibrillation – An observational cohort study among Norwegian patients with stable angina pectoris. Int J Cardiol, 317, 75-80.
19. Håglin, L., Domellöf, M., Bäckman, L., & Forsgren, L. (2020). Low plasma thiamine and phosphate in male patients with Parkinson’s disease is associated with mild cognitive impairment. Clin Nutr ESPEN, 37, 93-99.
20. Iversen, P. O., Atukunda, P., Kort, R., Ueland, P. M., Westerberg, A. C., & Muhoozi, G. K. M. (2020). No associations between microbiota signalling substances and cognitive, language and motor development among three-year-old rural Ugandan children. Acta Paediatr, 109(11), 2339-2341.
21. Solvik, B. S., Strand, T. A., Kvestad, I., Markhus, M. W., Ueland, P. M., McCann, A. et al. (2020). Dietary Intake and Biomarkers of Folate and Cobalamin Status in Norwegian Preschool Children: The FINS-KIDS Study. J Nutr, 150(7), 1852-1858.
22. Koenig, K. L., Scarmo, S., Afanasyeva, Y., Clendenen, T. V., Ueland, P. M., & Zeleniuch-Jacquotte, A. (2020). Circulating unmetabolized folic acid and 5-methyltetrahydrofolate and risk of breast cancer: a nested case-control study. Eur J Clin Nutr, 74(9), 1306-1315.
23. Bjørnestad, E. Ø., Olset, H., Dhar, I., Løland, K., Pedersen, E. K. R., Svingen, G. F. T. et al. (2020). Circulating trimethyllysine and risk of acute myocardial infarction in patients with suspected stable coronary heart disease. J Intern Med, 288(4), 446-456.
24. Huang, J. Y., Luu, H. N., Butler, L. M., Midttun, Ø., Ulvik, A., Wang, R. et al. (2020). A prospective evaluation of serum methionine-related metabolites in relation to pancreatic cancer risk in two prospective cohort studies. Int J Cancer, 147(7), 1917-1927.
25. Egorova, O., Myte, R., Schneede, J., Hägglöf, B., Bölte, S., Domellöf, E. et al. (2020). Maternal blood folate status during early pregnancy and occurrence of autism spectrum disorder in offspring: a study of 62 serum biomarkers. Mol Autism, 11(1), 7.
26. Ornosa-Martín, G., Fernandez-Ballart, J. D., Ceruelo, S., Ríos, L., Ueland, P. M., Meyer, K. et al. (2020). Homocysteine, the methylenetetrahydrofolate reductase 677C>T polymorphism and hypertension: effect modifiers by lifestyle factors and population subgroups. Br J Nutr, 1-11.
27. Lund, A., Nordrehaug, J. E., Slettom, G., Solvang, S. H., Pedersen, E. K., Midttun, Ø. et al. (2020). Correction: Plasma kynurenines and prognosis in patients with heart failure. PLoS One, 15(2), e0230056.
28.Kiblawi, R., Holowatyj, A. N., Gigic, B., Brezina, S., Geijsen, A. J. M. R., Ose, J. et al. (2020). One-carbon metabolites, B vitamins and associations with systemic inflammation and angiogenesis biomarkers among colorectal cancer patients: results from the ColoCare Study. Br J Nutr, 123(10), 1187-1200.
29. Cavallé-Busquets, P., Inglès-Puig, M., Fernandez-Ballart, J. D., Haro-Barceló, J., Rojas-Gómez, A., Ramos-Rodriguez, C. et al. (2020). Moderately elevated first trimester fasting plasma total homocysteine is associated with increased probability of miscarriage. The Reus-Tarragona Birth Cohort Study. Biochimie, 173, 62-67.
30. Fosså, A., Smeland, K. H., Fluge, Ø., Tronstad, K. J., Loge, J. H., Midttun, Ø. et al. (2020). Metabolic analysis of amino acids and vitamin B6 pathways in lymphoma survivors with cancer related chronic fatigue. PLoS One, 15(1), e0227384.
31. Lund, A., Nordrehaug, J. E., Slettom, G., Solvang, S. H., Pedersen, E. K., Midttun, Ø. et al. (2020). Plasma kynurenines and prognosis in patients with heart failure. PLoS One, 15(1), e0227365.
32. Crozier, S. R., Godfrey, K. M., Calder, P. C., Robinson, S. M., Inskip, H. M., Baird, J. et al. (2020). Vegetarian Diet during Pregnancy Is Not Associated with Poorer Cognitive Performance in Children at Age 6-7 Years. Nutrients, 11(12).
33. Bratlie, M., Hagen, I. V., Helland, A., Midttun, Ø., Ulvik, A., Rosenlund, G. et al. (2020). Five salmon dinners per week were not sufficient to prevent the reduction in serum vitamin D in autumn at 60° north latitude: a randomised trial. Br J Nutr, 123(4), 419-427.
34. Van Parys, A., Lysne, V., Svingen, G. F. T., Ueland, P. M., Dhar, I., Øyen, J. et al. (2020). Dietary choline is related to increased risk of acute myocardial infarction in patients with stable angina pectoris. Biochimie, 173, 68-75.
35. Mödinger, Y., Schön, C., Wilhelm, M., & Hals, P. A. (2020). Plasma Kinetics of Choline and Choline Metabolites After A Single Dose of SuperbaBoostTM Krill Oil or Choline Bitartrate in Healthy Volunteers. Nutrients, 11(10).
36. Lu, Y., Karagounis, L. G., Ng, T. P., Carre, C., Narang, V., Wong, G. et al. (2020). Systemic and Metabolic Signature of Sarcopenia in Community-Dwelling Older Adults. J Gerontol A Biol Sci Med Sci, 75(2), 309-317.
2019
1. Zuo, H., Ueland, P. M., Midttun, O., Tell, G. S., Fanidi, A., Zheng, W. et al. (2019). Vitamin B6 catabolism and lung cancer risk: results from the Lung Cancer Cohort Consortium (LC3). Ann Oncol, 30(3), 478-485.
2. Dhar, I., Lysne, V., Svingen, G. F. T., Ueland, P. M., Gregory, J. F., Bonaa, K. H. et al. (2019). Elevated plasma cystathionine is associated with increased risk of mortality among patients with suspected or established coronary heart disease. Am J Clin Nutr, 109(6), 1546-1554.
3. Ulven, S. M., Christensen, J. J., Nygard, O., Svardal, A., Leder, L., Ottestad, I. et al. (2019). Using metabolic profiling and gene expression analyses to explore molecular effects of replacing saturated fat with polyunsaturated fat-a randomized controlled dietary intervention study. Am J Clin Nutr, 109(5), 1239-1250.
4. Lindquist, C., Bjorndal, B., Lund, A., Slettom, G., Skorve, J., Nygard, O. et al. (2019). Increased fatty acid oxidation and mitochondrial proliferation in liver are associated with increased plasma kynurenine metabolites and nicotinamide levels in normolipidemic and carnitine-depleted rats. Biochim Biophys Acta Mol Cell Biol Lipids, 1865(2), 158543.
5. Lai, J. S., Mohamad Ayob, M. N., Cai, S., Quah, P. L., Gluckman, P. D., Shek, L. P. et al. (2019). Maternal plasma vitamin B12 concentrations during pregnancy and infant cognitive outcomes at 2 years of age. Br J Nutr, 121(11), 1303-1312.
6. Drotningsvik, A., Midttun, O., Vikoren, L. A., McCann, A., Ueland, P. M., Mellgren, G. et al. (2019). Urine and plasma concentrations of amino acids and plasma vitamin status differ, and are differently affected by salmon intake, in obese Zucker fa/fa rats with impaired kidney function and in Long-Evans rats with healthy kidneys. Br J Nutr, 122(3), 262-273.
7. Bratlie, M., Hagen, I. V., Helland, A., Midttun, O., Ulvik, A., Rosenlund, G. et al. (2019). Five salmon dinners per week were not sufficient to prevent the reduction in serum vitamin D in autumn at 60 degrees north latitude: a randomised trial. Br J Nutr, 123(4), 419-427.L
8. Solvang, S. H., Nordrehaug, J. E., Tell, G. S., Nygard, O., McCann, A., Ueland, P. M. et al. (2019). The kynurenine pathway and cognitive performance in community-dwelling older adults. The Hordaland Health Study. Brain Behav Immun, 75, 155-162.
9. Ryan, K. M., Allers, K. A., McLoughlin, D. M., & Harkin, A. (2019). Tryptophan metabolite concentrations in depressed patients before and after electroconvulsive therapy. Brain Behav Immun, 83, 153-162.
10. Hildre, A. S., Solvang, S. H., Aarsland, D., Midtun, O., McCann, A., Ervik, A. O. et al. (2019). Components of the choline oxidation pathway modify the association between the apolipoprotein epsilon4 gene variant and cognitive decline in patients with dementia. Brain Res, 1726, 146519.
11. Aarsland, T. I., Leskauskaite, I., Midttun, O., Ulvik, A., Ueland, P. M., Oltedal, L. et al. (2019). The effect of electroconvulsive therapy (ECT) on serum tryptophan metabolites. Brain Stimul, 12(5), 1135-1142.
12. Thomas, C. E., Wang, R., Adams-Haduch, J., Murphy, S. E., Ueland, P. M., Midttun, O. et al. (2019). Urinary Cotinine Is as Good a Biomarker as Serum Cotinine for Cigarette Smoking Exposure and Lung Cancer Risk Prediction. Cancer Epidemiol Biomarkers Prev, 29(1), 127-132.
13. McCann, A., Giil, L. M., Ulvik, A., Seifert, R., Rebnord, E. W., Pedersen, E. R. et al. (2019). Plasma Amino Acids and Incident Type 2 Diabetes in Patients With Coronary Artery Disease. Diabetes Care, 42(7), 1225-1233.
14. Marild, K., Tapia, G., Midttun, O., Ueland, P. M., Magnus, M. C., Rewers, M. et al. (2019). Smoking in pregnancy, cord blood cotinine and risk of celiac disease diagnosis in offspring. Eur J Epidemiol, 34(7), 637-649.
15. Hovland, I. H., Leikanger, I. S., Stokkeland, O., Waage, K. H., Mjos, S. A., Brokstad, K. A. et al. (2019). Effects of low doses of fish and milk proteins on glucose regulation and markers of insulin sensitivity in overweight adults: a randomised, double blind study. Eur J Nutr.
16. Hagen, I. V., Helland, A., Bratlie, M., Midttun, O., McCann, A., Sveier, H. et al. (2019). TMAO, creatine and 1-methylhistidine in serum and urine are potential biomarkers of cod and salmon intake: a randomised clinical trial in adults with overweight or obesity. Eur J Nutr.
17. Olsen, T., Vinknes, K. J., Blomhoff, R., Lysne, V., Midttun, O., Dhar, I. et al. (2019). Creatinine, total cysteine and uric acid are associated with serum retinol in patients with cardiovascular disease. Eur J Nutr.
18. Bassett, J. K., Brinkman, M. T., Dugue, P. A., Ueland, P. M., Midttun, O., Ulvik, A. et al. (2019). Circulating concentrations of B group vitamins and urothelial cell carcinoma. Int J Cancer, 144(8), 1909-1917.
19. Geijsen, A. J. M. R., Brezina, S., Keski-Rahkonen, P., Baierl, A., Bachleitner-Hofmann, T., Bergmann, M. M. et al. (2019). Plasma metabolites associated with colorectal cancer: A discovery-replication strategy. Int J Cancer, 145(5), 1221-1231.
20. Fanidi, A., Carreras-Torres, R., Larose, T. L., Yuan, J. M., Stevens, V. L., Weinstein, S. J. et al. (2019). Is high vitamin B12 status a cause of lung cancer. Int J Cancer, 145(6), 1499-1503.
21. Geijsen, A. J. M. R., van Roekel, E. H., van Duijnhoven, F. J. B., Achaintre, D., Bachleitner-Hofmann, T., Baierl, A. et al. (2019). Plasma metabolites associated with colorectal cancer stage: Findings from an international consortium. Int J Cancer.
22. Huang, J. Y., Larose, T. L., Luu, H. N., Wang, R., Fanidi, A., Alcala, K. et al. (2019). Circulating markers of cellular immune activation in prediagnostic blood sample and lung cancer risk in the Lung Cancer Cohort Consortium (LC3). Int J Cancer, 146(9), 2394-2405.
23. Solvang, S. H., Nordrehaug, J. E., Aarsland, D., Lange, J., Ueland, P. M., McCann, A. et al. (2019). Kynurenines, Neuropsychiatric Symptoms, and Cognitive Prognosis in Patients with Mild Dementia. Int J Tryptophan Res, 12, 1178646919877883.
24. Ervik, A. O., Solvang, S. H., Nordrehaug, J. E., Ueland, P. M., Midttun, O., Hildre, A. et al. (2019). The Associations Between Cognitive Prognosis and Kynurenines Are Modified by the Apolipoprotein epsilon4 Allele Variant in Patients With Dementia. Int J Tryptophan Res, 12, 1178646919885637.
25. Rezahosseini, O., Knudsen, A. D., Gelpi, M., Ronit, A., Ueland, P. M., Midttun, O. et al. (2019). Plasma Cotinine Cutoff for Distinguishing Smokers From Nonsmokers Among Persons Living With HIV. J Acquir Immune Defic Syndr, 82(5), e54-e56.
26. Borowczyk, K., Piechocka, J., Glowacki, R., Dhar, I., Midtun, O., Tell, G. S. et al. (2019). Urinary excretion of homocysteine thiolactone and the risk of acute myocardial infarction in coronary artery disease patients: the WENBIT trial. J Intern Med, 285(2), 232-244.
27. Sande, J. S., Ulvik, A., Midttun, O., Ueland, P. M., Hammer, H. B., Valen, M. et al. (2019). Vitamin B-6 Status Correlates with Disease Activity in Rheumatoid Arthritis Patients During Treatment with TNFalpha Inhibitors. J Nutr, 149(5), 770-775.
28. Stevelink, R., Pangilinan, F., Jansen, F. E., Braun, K. P. J., International, L. A. E. C. O. C. E., Molloy, A. M. et al. (2019). Assessing the genetic association between vitamin B6 metabolism and genetic generalized epilepsy. Mol Genet Metab Rep, 21, 100518
29. Mödinger, Y., Schön, C., Wilhelm, M., & Hals, P. A. (2019). Plasma Kinetics of Choline and Choline Metabolites After A Single Dose of SuperbaBoostTM Krill Oil or Choline Bitartrate in Healthy Volunteers. Nutrients, 11(10).
30. Lysne, V., Bjorndal, B., Grinna, M. L., Midttun, O., Ueland, P. M., Berge, R. K. et al. (2019). Short-term treatment with a peroxisome proliferator-activated receptor alpha agonist influences plasma one-carbon metabolites and B-vitamin status in rats. PLoS One, 14(12), e0226069.
31. Quist-Paulsen, E., Ormaasen, V., Kran, A. B., Dunlop, O., Ueland, P. M., Ueland, T. et al. (2019). Encephalitis and aseptic meningitis: short-term and long-term outcome, quality of life and neuropsychological functioning. Sci Rep, 9(1), 16158.
32. Burri, L., Heggen, K., & Storsve, A. B. (2019). Phosphatidylcholine from krill increases plasma choline and its metabolites in dogs. Vet World, 12(5), 671-676.
33. Van Parys, A., Lysne, V., Svingen, G. F. T., Ueland, P. M., Dhar, I., Oyen, J. et al. (2019). Dietary choline is related to increased risk of acute myocardial infarction in patients with stable angina pectoris. Biochimie.
34. Muller, D. C., Larose, T. L., Hodge, A., Guida, F., Langhammer, A., Grankvist, K. et al. (2019). Circulating high sensitivity C reactive protein concentrations and risk of lung cancer: nested case-control study within Lung Cancer Cohort Consortium. BMJ, 364, k4981.
2018
1. Fanidi, A., Muller, D.C., Yuan, J.M., Stevens, V.L., Weinstein, S.J., Albanes, D., Prentice, R., Thomsen, C.A., Pettinger, M., Cai, Q., et al. (2018). Circulating Folate, Vitamin B6, and Methionine in Relation to Lung Cancer Risk in the Lung Cancer Cohort Consortium (LC3). Journal of the National Cancer Institute 110: djx119.
2. Zuo, H., Nygard, O., Vollset, S.E., Ueland, P.M., Ulvik, A., Midttun, O., Meyer, K., Igland, J., Sulo, G., and Tell, G.S. (2018). Smoking, plasma cotinine and risk of atrial fibrillation: the Hordaland Health Study. Journal of internal medicine 283, 73-82.
3. Zuo, H., Ueland, P.M., Midttun, O., Vollset, S.E., Tell, G.S., Theofylaktopoulou, D., Travis, R.C., Boutron-Ruault, M.C., Fournier, A., Severi, G., et al. (2018). Results from the European Prospective Investigation into Cancer and Nutrition Link Vitamin B6 Catabolism and Lung Cancer Risk. Cancer research 78, 302-308.
4. Theofylaktopoulou, D., Midttun, O., Ueland, P.M., Meyer, K., Fanidi, A., Zheng, W., Shu, X.O., Xiang, Y.B., Prentice, R., Pettinger, M., et al. (2018). Impaired functional vitamin B6 status is associated with increased risk of lung cancer. International journal of cancer 142, 2425-2434.
5. Degerud, E., Nygard, O., de Vogel, S., Hoff, R., Svingen, G.F.T., Pedersen, E.R., Nilsen, D.W.T., Nordrehaug, J.E., Midttun, O., Ueland, P.M., et al. (2018). Plasma 25-Hydroxyvitamin D and Mortality in Patients With Suspected Stable Angina Pectoris. The Journal of clinical endocrinology and metabolism 103, 1161-1170.
6. Zuo, H., Tell, G.S., Ueland, P.M., Nygard, O., Vollset, S.E., Midttun, O., Meyer, K., and Ulvik, A. (2018). The PAr index, an indicator reflecting altered vitamin B-6 homeostasis, is associated with long-term risk of stroke in the general population: the Hordaland Health Study (HUSK). The American journal of clinical nutrition 107, 105-112.
7. Christensen, M.H.E., Fadnes, D.J., Rost, T.H., Pedersen, E.R., Andersen, J.R., Vage, V., Ulvik, A., Midttun, O., Ueland, P.M., Nygard, O.K., et al. (2018). Inflammatory markers, the tryptophan-kynurenine pathway, and vitamin B status after bariatric surgery. PloS one 13, e0192169.
8. Agudelo, L.Z., Ferreira, D.M.S., Cervenka, I., Bryzgalova, G., Dadvar, S., Jannig, P.R., Pettersson-Klein, A.T., Lakshmikanth, T., Sustarsic, E.G., Porsmyr-Palmertz, M., et al. (2018). Kynurenic Acid and Gpr35 Regulate Adipose Tissue Energy Homeostasis and Inflammation. Cell metabolism 27, 378-392 e375.
9. Gao, J., Meyer, K., Borucki, K., and Ueland, P.M. (2018). Multiplex Immuno-MALDI-TOF MS for Targeted Quantification of Protein Biomarkers and Their Proteoforms Related to Inflammation and Renal Dysfunction. Analytical chemistry 90, 3366-3373.
10. Mjelva, O.R., Svingen, G.F.T., Pedersen, E.K.R., Seifert, R., Kvaloy, J.T., Midttun, O., Ueland, P.M., Nordrehaug, J.E., Nygard, O., and Nilsen, D.W.T. (2018). Fibrinogen and Neopterin Is Associated with Future Myocardial Infarction and Total Mortality in Patients with Stable Coronary Artery Disease. Thrombosis and haemostasis 118, 778-790.
11. Sole-Navais, P., Salat-Batlle, J., Cavalle-Busquets, P., Fernandez-Ballart, J., Ueland, P.M., Ballesteros, M., Ornosa-Martin, G., Ingles-Puig, M., Colomina, J.M., and Murphy, M.M. (2018). Early pregnancy folate-cobalamin interactions and their effects on cobalamin status and hematologic variables throughout pregnancy. The American journal of clinical nutrition 107, 173-182.
12. Brosnan, J.T., Mills, J.L., Ueland, P.M., Shane, B., Fan, R., Chiu, C.Y., Pangilinan, F., Brody, L.C., Brosnan, M.E., Pongnopparat, T., et al. (2018). Lifestyle, metabolite, and genetic determinants of formate concentrations in a cross-sectional study in young, healthy adults. The American journal of clinical nutrition 107, 345-354.
13. Zuo, H., Nygard, O., Ueland, P.M., Vollset, S.E., Svingen, G.F.T., Pedersen, E.R., Midttun, O., Meyer, K., Nordrehaug, J.E., Nilsen, D.W.T., et al. (2018). Association of plasma neopterin with risk of an inpatient hospital diagnosis of atrial fibrillation: results from two prospective cohort studies. Journal of internal medicine 283, 578-587.
14. Muller, D.C., Hodge, A.M., Fanidi, A., Albanes, D., Mai, X.M., Shu, X.O., Weinstein, S.J., Larose, T.L., Zhang, X., Han, J., et al. (2018). No association between circulating concentrations of vitamin D and risk of lung cancer: an analysis in 20 prospective studies in the Lung Cancer Cohort Consortium (LC3). Annals of oncology : official journal of the European Society for Medical Oncology 29, 1468-1475.
17. Dhar, I., Lysne, V., Seifert, R., Svingen, G.F.T., Ueland, P.M., and Nygard, O.K. (2018). Plasma methionine and risk of acute myocardial infarction: Effect modification by established risk factors. Atherosclerosis 272, 175-181.
18. Zuo, H., Svingen, G.F.T., Tell, G.S., Ueland, P.M., Vollset, S.E., Pedersen, E.R., Ulvik, A., Meyer, K., Nordrehaug, J.E., Nilsen, D.W.T., et al. (2018). Plasma Concentrations and Dietary Intakes of Choline and Betaine in Association With Atrial Fibrillation Risk: Results From 3 Prospective Cohorts With Different Health Profiles. Journal of the American Heart Association 7: e008190.
19. Myte, R., Gylling, B., Haggstrom, J., Schneede, J., Lofgren-Burstrom, A., Huyghe, J.R., Hallmans, G., Meyer, K., Johansson, I., Ueland, P.M., et al. (2018). One-carbon metabolism biomarkers and genetic variants in relation to colorectal cancer risk by KRAS and BRAF mutation status. PloS one 13, e0196233.
20. Hoel, H., Hove-Skovsgaard, M., Hov, J.R., Gaardbo, J.C., Holm, K., Kummen, M., Rudi, K., Nwosu, F., Valeur, J., Gelpi, M., et al. (2018). Impact of HIV and Type 2 diabetes on Gut Microbiota Diversity, Tryptophan Catabolism and Endothelial Dysfunction. Scientific reports 8, 6725.
21. Parr, C.L., Magnus, M.C., Karlstad, O., Holvik, K., Lund-Blix, N.A., Haugen, M., Page, C.M., Nafstad, P., Ueland, P.M., London, S.J., et al. (2018). Vitamin A and D intake in pregnancy, infant supplementation, and asthma development: the Norwegian Mother and Child Cohort. The American journal of clinical nutrition 107, 789-798.
22. Dhar, I., Svingen, G.F.T., Pedersen, E.R., DeRatt, B., Ulvik, A., Strand, E., Ueland, P.M., Bonaa, K.H., Gregory, J.F., and Nygard, O.K. (2018). Plasma cystathionine and risk of acute myocardial infarction among patients with coronary heart disease: Results from two independent cohorts. International journal of cardiology 266, 24-30.
23. Huang, J.Y., Butler, L.M., Midttun, O., Ulvik, A., Wang, R., Jin, A., Gao, Y.T., Ueland, P.M., Koh, W.P., and Yuan, J.M. (2018). A prospective evaluation of serum kynurenine metabolites and risk of pancreatic cancer. PloS one 13, e0196465.
24. Midttun, O., Ulvik, A., Nygard, O., and Ueland, P.M. (2018). Performance of plasma trigonelline as a marker of coffee consumption in an epidemiologic setting. The American journal of clinical nutrition 107, 941-947.
25. Chandyo, R.K., Ulak, M., Kvestad, I., Hysing, M., Shrestha, M., Ranjitkar, S., Ulvik, A., Ueland, P.M., Shrestha, L., and Strand, T.A. (2018). Cobalamin and Folate Status among Breastfed Infants in Bhaktapur, Nepal. Nutrients 10.
26. Gylling, B., Myte, R., Ulvik, A., Ueland, P.M., Midttun, O., Schneede, J., Hallmans, G., Haggstrom, J., Johansson, I., Van Guelpen, B., et al. (2019). One-carbon metabolite ratios as functional B-vitamin markers and in relation to colorectal cancer risk. International journal of cancer 144, 947-956.
27. Larose, T.L., Guida, F., Fanidi, A., Langhammer, A., Kveem, K., Stevens, V.L., Jacobs, E.J., Smith-Warner, S.A., Giovannucci, E., Albanes, D., et al. (2018). Circulating cotinine concentrations and lung cancer risk in the Lung Cancer Cohort Consortium (LC3). International journal of epidemiology 47, 1760-1771.
28. Varsi, K., Ueland, P.M., Torsvik, I.K., and Bjorke-Monsen, A.L. (2018). Maternal Serum Cobalamin at 18 Weeks of Pregnancy Predicts Infant Cobalamin Status at 6 Months-A Prospective, Observational Study. The Journal of nutrition 148, 738-745.
29. Svingen, G.F.T., Zuo, H., Ueland, P.M., Seifert, R., Loland, K.H., Pedersen, E.R., Schuster, P.M., Karlsson, T., Tell, G.S., Schartum-Hansen, H., et al. (2018). Increased plasma trimethylamine-N-oxide is associated with incident atrial fibrillation. International journal of cardiology 267, 100-106.
30. Strand, T.A., Ulak, M., Kvestad, I., Henjum, S., Ulvik, A., Shrestha, M., Thorne-Lyman, A.L., Ueland, P.M., Shrestha, P.S., and Chandyo, R.K. (2018). Maternal and infant vitamin B12 status during infancy predict linear growth at 5 years. Pediatric research 84, 611-618.
31. O’Reilly, J., Pangilinan, F., Hokamp, K., Ueland, P.M., Brosnan, J.T., Brosnan, M.E., Brody, L.C., and Molloy, A.M. (2018). The impact of common genetic variants in the mitochondrial glycine cleavage system on relevant metabolites. Molecular genetics and metabolism reports 16, 20-22.
32. Olsen, T., Vinknes, K.J., Svingen, G.F., Pedersen, E.R., Dhar, I., Tell, G.S., Blomhoff, R., Ueland, P.M., Midttun, O., Refsum, H., et al. (2018). The risk association of plasma total homocysteine with acute myocardial infarction is modified by serum vitamin A. European journal of preventive cardiology 25, 1612-1620.
33. Magnus, M.C., Tapia, G., Olsen, S.F., Granstrom, C., Marild, K., Ueland, P.M., Midttun, O., Svensson, J., Johannesen, J., Skrivarhaug, T., et al. (2018). Parental Smoking and Risk of Childhood-onset Type 1 Diabetes. Epidemiology 29, 848-856.
34. Helm, T., Varsi, K., Flotre, C.H., Lund, A., Svingen, G.F.T., Ueland, P.M., and Bjorke-Monsen, A.L. (2018). Plasma Homoarginine Concentrations According to Use of Hormonal Contraception. Scientific reports 8, 12217.
35. Drotningsvik, A., Midttun, O., McCann, A., Ueland, P.M., Hogoy, I., and Gudbrandsen, O.A. (2018). Dietary intake of cod protein beneficially affects concentrations of urinary markers of kidney function and results in lower urinary loss of amino acids in obese Zucker fa/fa rats. The British journal of nutrition 120, 740-750.
36. Borowczyk, K., Piechocka, J., Glowacki, R., Dhar, I., Midtun, O., Tell, G.S., Ueland, P.M., Nygard, O., and Jakubowski, H. (2019). Urinary excretion of homocysteine thiolactone and the risk of acute myocardial infarction in coronary artery disease patients: the WENBIT trial. Journal of internal medicine 285, 232-244.
37. Bjorndal, B., Bruheim, I., Lysne, V., Ramsvik, M.S., Ueland, P.M., Nordrehaug, J.E., Nygard, O.K., and Berge, R.K. (2018). Plasma choline, homocysteine and vitamin status in healthy adults supplemented with krill oil: a pilot study. Scandinavian journal of clinical and laboratory investigation 78, 527-532.
38. Vollsaeter, M., Halvorsen, T., Markestad, T., Oymar, K., Ueland, P.M., Meyer, K., Midttun, O., and Bjorke-Monsen, A.L. (2018). Renal function and blood pressure in 11 year old children born extremely preterm or small for gestational age. PloS one 13, e0205558.
39. Bassett, J.K., Brinkman, M.T., Dugue, P.A., Ueland, P.M., Midttun, O., Ulvik, A., Bolton, D., Southey, M.C., English, D.R., Milne, R.L., et al. (2019). Circulating concentrations of B group vitamins and urothelial cell carcinoma. International journal of cancer 144, 1909-1917.
40. Shane, B., Pangilinan, F., Mills, J.L., Fan, R., Gong, T., Cropp, C.D., Kim, Y., Ueland, P.M., Bailey-Wilson, J.E., Wilson, A.F., et al. (2018). The 677C–>T variant of MTHFR is the major genetic modifier of biomarkers of folate status in a young, healthy Irish population. The American journal of clinical nutrition 108, 1334-1341.
41. Dhar, I., Svingen, G.F.T., Ueland, P.M., Lysne, V., Svenningsson, M.M., Tell, G.S., and Nygard, O.K. (2018). Plasma Cystathionine and Risk of Incident Stroke in Patients With Suspected Stable Angina Pectoris. Journal of the American Heart Association 7, e008824.
42. Quist-Paulsen, E., Aukrust, P., Kran, A.B., Dunlop, O., Ormaasen, V., Stiksrud, B., Midttun, O., Ueland, T., Ueland, P.M., Mollnes, T.E., et al. (2018). High neopterin and IP-10 levels in cerebrospinal fluid are associated with neurotoxic tryptophan metabolites in acute central nervous system infections. Journal of neuroinflammation 15, 327.
43. Lund, A., Giil, L.M., Slettom, G., Nygaard, O., Heidecke, H., and Nordrehaug, J.E. (2018). Antibodies to receptors are associated with biomarkers of inflammation and myocardial damage in heart failure. International journal of cardiology 250, 253-259.
44. Bjork, M., Riedel, B., Spigset, O., Veiby, G., Kolstad, E., Daltveit, A.K., and Gilhus, N.E. (2018). Association of Folic Acid Supplementation During Pregnancy With the Risk of Autistic Traits in Children Exposed to Antiepileptic Drugs In Utero. JAMA neurology 75, 160-168.
45. Doolin, K., Allers, K.A., Pleiner, S., Liesener, A., Farrell, C., Tozzi, L., O’Hanlon, E., Roddy, D., Frodl, T., Harkin, A., et al. (2018). Altered tryptophan catabolite concentrations in major depressive disorder and associated changes in hippocampal subfield volumes. Psychoneuroendocrinology 95, 8-17.
46. Lai, J.S., Pang, W.W., Cai, S., Lee, Y.S., Chan, J.K.Y., Shek, L.P.C., Yap, F.K.P., Tan, K.H., Godfrey, K.M., van Dam, R.M., et al. (2018). High folate and low vitamin B12 status during pregnancy is associated with gestational diabetes mellitus. Clinical nutrition 37, 940-947.
2017
1. Bjorke-Jenssen, A., Ueland, P. M., and Bjorke-Monsen, A. L. (2017) Amniotic Fluid Arginine from Gestational Weeks 13 to 15 Is a Predictor of Birth Weight, Length, and Head Circumference. Nutrients 9
2. Theofylaktopoulou, D., Midttun, O., Ueland, P. M., Meyer, K., Fanidi, A., Zheng, W., Shu, X. O., Xiang, Y. B., Prentice, R., Pettinger, M., Thomson, C. A., Giles, G. G., Hodge, A., Cai, Q., Blot, W. J., Wu, J., Johansson, M., Hultdin, J., Grankvist, K., Stevens, V. L., McCullough, M. M., Weinstein, S. J., Albanes, D., Ziegler, R., Freedman, N. D., Langhammer, A., Hveem, K., Naess, M., Sesso, H. D., Gaziano, J. M., Buring, J. E., Lee, I. M., Severi, G., Zhang, X., Stampfer, M. J., Han, J., Smith-Warner, S. A., Zeleniuch-Jacquotte, A., Le Marchand, L., Yuan, J. M., Wang, R., Butler, L. M., Koh, W. P., Gao, Y. T., Rothman, N., Ericson, U., Sonestedt, E., Visvanathan, K., Jones, M. R., Relton, C., Brennan, P., Johansson, M., and Ulvik, A. (2017) Impaired functional vitamin B6 status is associated with increased risk of lung cancer. International journal of cancer 142:2425-34.
3. Bjornestad, E. O., Borsholm, R. A., Svingen, G. F. T., Pedersen, E. R., Seifert, R., Midttun, O., Ueland, P. M., Tell, G. S., Bonaa, K. H., and Nygard, O. (2017) Neopterin as an Effect Modifier of the Cardiovascular Risk Predicted by Total Homocysteine: A Prospective 2-Cohort Study. Journal of the American Heart Association 6
4. Ntzouvani, A., Nomikos, T., Panagiotakos, D., Fragopoulou, E., Pitsavos, C., McCann, A., Ueland, P. M., and Antonopoulou, S. (2017) Amino acid profile and metabolic syndrome in a male Mediterranean population: A cross-sectional study. Nutrition, metabolism, and cardiovascular diseases : NMCD 27, 1021-1030
5. Zuo, H., Nygard, O., Vollset, S. E., Ueland, P. M., Ulvik, A., Midttun, O., Meyer, K., Igland, J., Sulo, G., and Tell, G. S. (2018) Smoking, plasma cotinine and risk of atrial fibrillation: the Hordaland Health Study. Journal of internal medicine 283, 73-82
6. Giil, L. M., Midttun, O., Refsum, H., Ulvik, A., Advani, R., Smith, A. D., and Ueland, P. M. (2017) Kynurenine Pathway Metabolites in Alzheimer’s Disease. Journal of Alzheimer’s disease : JAD 60, 495-504
7. DeRatt, B. N., Ralat, M. A., Lysne, V., Tayyari, F., Dhar, I., Edison, A. S., Garrett, T. J., Midttun, O., Ueland, P. M., Nygard, O. K., and Gregory, J. F., 3rd. (2017) Metabolomic Evaluation of the Consequences of Plasma Cystathionine Elevation in Adults with Stable Angina Pectoris. The Journal of nutrition 147, 1658-1668
8. Olsen, T., Vinknes, K. J., Svingen, G. F. T., Pedersen, E. R., Tell, G. S., Blomhoff, R., Drevon, C. A., Ueland, P. M., Midttun, O., Refsum, H., and Nygard, O. K. (2017) Cardiovascular disease risk associated with serum apolipoprotein B is modified by serum vitamin A. Atherosclerosis 265, 325-330
9. Green, R., Allen, L. H., Bjorke-Monsen, A. L., Brito, A., Gueant, J. L., Miller, J. W., Molloy, A. M., Nexo, E., Stabler, S., Toh, B. H., Ueland, P. M., and Yajnik, C. (2017) Correction: Vitamin B12 deficiency. Nature reviews. Disease primers 3, 17054
10. McCann, A., Midttun, O., Whitfield, K. C., Kroeun, H., Borath, M., Sophonneary, P., Ueland, P. M., and Green, T. J. (2017) Comparable Performance Characteristics of Plasma Thiamine and Erythrocyte Thiamine Diphosphate in Response to Thiamine Fortification in Rural Cambodian Women. Nutrients 9
11. Green, R., Allen, L. H., Bjorke-Monsen, A. L., Brito, A., Gueant, J. L., Miller, J. W., Molloy, A. M., Nexo, E., Stabler, S., Toh, B. H., Ueland, P. M., and Yajnik, C. (2017) Vitamin B12 deficiency. Nature reviews. Disease primers 3, 17040
12. Rebnord, E. W., Strand, E., Midttun, O., Svingen, G. F. T., Christensen, M. H. E., Ueland, P. M., Mellgren, G., Njolstad, P. R., Tell, G. S., Nygard, O. K., and Pedersen, E. R. (2017) The kynurenine:tryptophan ratio as a predictor of incident type 2 diabetes mellitus in individuals with coronary artery disease. Diabetologia 60, 1712-1721
13. Rees, J. R., Morris, C. B., Peacock, J. L., Ueland, P. M., Barry, E. L., McKeown-Eyssen, G. E., Figueiredo, J. C., Snover, D. C., and Baron, J. A. (2017) Unmetabolized Folic Acid, Tetrahydrofolate, and Colorectal Adenoma Risk. Cancer prevention research 10, 451-458
14. Garcia Lopez, M., Bonaa, K. H., Ebbing, M., Eriksen, E. F., Gjesdal, C. G., Nygard, O., Tell, G. S., Ueland, P. M., and Meyer, H. E. (2017) B Vitamins and Hip Fracture: Secondary Analyses and Extended Follow-Up of Two Large Randomized Controlled Trials. Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 32, 1981-1989
15. Gelpi, M., Hartling, H. J., Ueland, P. M., Ullum, H., Troseid, M., and Nielsen, S. D. (2017) Tryptophan catabolism and immune activation in primary and chronic HIV infection. BMC infectious diseases 17, 349
16. Midttun, O., Theofylaktopoulou, D., McCann, A., Fanidi, A., Muller, D. C., Meyer, K., Ulvik, A., Zheng, W., Shu, X. O., Xiang, Y. B., Prentice, R., Thomson, C. A., Pettinger, M., Giles, G. G., Hodge, A., Cai, Q., Blot, W. J., Wu, J., Johansson, M., Hultdin, J., Grankvist, K., Stevens, V. L., McCullough, M. L., Weinstein, S. J., Albanes, D., Langhammer, A., Hveem, K., Naess, M., Sesso, H. D., Gaziano, J. M., Buring, J. E., Lee, I. M., Severi, G., Zhang, X., Han, J., Stampfer, M. J., Smith-Warner, S. A., Zeleniuch-Jacquotte, A., le Marchand, L., Yuan, J. M., Butler, L. M., Koh, W. P., Wang, R., Gao, Y. T., Ericson, U., Sonestedt, E., Ziegler, R. G., Freedman, N. D., Visvanathan, K., Jones, M. R., Relton, C., Brennan, P., Johansson, M., and Ueland, P. M. (2017) Circulating concentrations of biomarkers and metabolites related to vitamin status, one-carbon and the kynurenine pathways in US, Nordic, Asian, and Australian populations. The American journal of clinical nutrition 105, 1314-1326
17. Ulvik, A., Hustad, S., McCann, A., Midttun, O., Nygard, O. K., and Ueland, P. M. (2017) Ratios of One-Carbon Metabolites Are Functional Markers of B-Vitamin Status in a Norwegian Coronary Angiography Screening Cohort. The Journal of nutrition 147, 1167-1173
18. Kvestad, I., Hysing, M., Shrestha, M., Ulak, M., Thorne-Lyman, A. L., Henjum, S., Ueland, P. M., Midttun, O., Fawzi, W., Chandyo, R. K., Shrestha, P. S., and Strand, T. A. (2017) Vitamin B-12 status in infancy is positively associated with development and cognitive functioning 5 y later in Nepalese children. The American journal of clinical nutrition 105, 1122-1131
19. Gylling, B., Myte, R., Schneede, J., Hallmans, G., Haggstrom, J., Johansson, I., Ulvik, A., Ueland, P. M., Van Guelpen, B., and Palmqvist, R. (2017) Vitamin B-6 and colorectal cancer risk: a prospective population-based study using 3 distinct plasma markers of vitamin B-6 status. The American journal of clinical nutrition 105, 897-904
20. Oyen, J., Gjesdal, C. G., Karlsson, T., Svingen, G. F., Tell, G. S., Strand, E., Drevon, C. A., Vinknes, K. J., Meyer, K., Ueland, P. M., and Nygard, O. (2017) Dietary Choline Intake Is Directly Associated with Bone Mineral Density in the Hordaland Health Study. The Journal of nutrition 147, 572-578
21. Marild, K., Vistnes, M., Tapia, G., Midttun, O., Ueland, P. M., Viken, M. K., Magnus, P., Berg, J. P., Stene, L. C., and Stordal, K. (2017) Midpregnancy and cord blood immunologic biomarkers, HLA genotype, and pediatric celiac disease. The Journal of allergy and clinical immunology 139, 1696-1698
22. Ueland, P. M., McCann, A., Midttun, O., and Ulvik, A. (2017) Inflammation, vitamin B6 and related pathways. Molecular aspects of medicine 53, 10-27
23. Bjorke-Monsen, A. L., Vollsaeter, M., Ueland, P. M., Markestad, T., Oymar, K., and Halvorsen, T. (2017) Increased Bronchial Hyperresponsiveness and Higher Asymmetric Dimethylarginine Levels after Fetal Growth Restriction. American journal of respiratory cell and molecular biology 56, 83-89
24. Parr, C. L., Magnus, M. C., Karlstad, O., Haugen, M., Refsum, H., Ueland, P. M., McCann, A., Nafstad, P., Haberg, S. E., Nystad, W., and London, S. J. (2017) Maternal Folate Intake during Pregnancy and Childhood Asthma in a Population-based Cohort. American journal of respiratory and critical care medicine 195, 221-228
25. Reese, S. E., Zhao, S., Wu, M. C., Joubert, B. R., Parr, C. L., Haberg, S. E., Ueland, P. M., Nilsen, R. M., Midttun, O., Vollset, S. E., Peddada, S. D., Nystad, W., and London, S. J. (2017) DNA Methylation Score as a Biomarker in Newborns for Sustained Maternal Smoking during Pregnancy. Environmental health perspectives 125, 760-766
26. Karlsson, T., Strand, E., Dierkes, J., Drevon, C. A., Oyen, J., Midttun, O., Ueland, P. M., Gudbrandsen, O. A., Pedersen, E. R., and Nygard, O. (2017) Associations between intake of fish and n-3 long-chain polyunsaturated fatty acids and plasma metabolites related to the kynurenine pathway in patients with coronary artery disease. European journal of nutrition 56, 261-272
27. Matejcic, M., de Batlle, J., Ricci, C., Biessy, C., Perrier, F., Huybrechts, I., Weiderpass, E., Boutron-Ruault, M. C., Cadeau, C., His, M., Cox, D. G., Boeing, H., Fortner, R. T., Kaaks, R., Lagiou, P., Trichopoulou, A., Benetou, V., Tumino, R., Panico, S., Sieri, S., Palli, D., Ricceri, F., Bueno-de-Mesquita, H. B., Skeie, G., Amiano, P., Sanchez, M. J., Chirlaque, M. D., Barricarte, A., Quiros, J. R., Buckland, G., van Gils, C. H., Peeters, P. H., Key, T. J., Riboli, E., Gylling, B., Zeleniuch-Jacquotte, A., Gunter, M. J., Romieu, I., and Chajes, V. (2017) Biomarkers of folate and vitamin B12 and breast cancer risk: report from the EPIC cohort. International journal of cancer 140, 1246-1259
28. Hughes, C. F., Ward, M., Tracey, F., Hoey, L., Molloy, A. M., Pentieva, K., and McNulty, H. (2017) B-Vitamin Intake and Biomarker Status in Relation to Cognitive Decline in Healthy Older Adults in a 4-Year Follow-Up Study. Nutrients 9
2016
1. Hughes, C. F., Ward, M., Tracey, F., Hoey, L., Molloy, A. M., Pentieva, K., and McNulty, H. (2017) B-Vitamin Intake and Biomarker Status in Relation to Cognitive Decline in Healthy Older Adults in a 4-Year Follow-Up Study. Nutrients 9
2. Fluge, O., Mella, O., Bruland, O., Risa, K., Dyrstad, S. E., Alme, K., Rekeland, I. G., Sapkota, D., Rosland, G. V., Fossa, A., Ktoridou-Valen, I., Lunde, S., Sorland, K., Lien, K., Herder, I., Thurmer, H., Gotaas, M. E., Baranowska, K. A., Bohnen, L. M., Schafer, C., McCann, A., Sommerfelt, K., Helgeland, L., Ueland, P. M., Dahl, O., and Tronstad, K. J. (2016) Metabolic profiling indicates impaired pyruvate dehydrogenase function in myalgic encephalopathy/chronic fatigue syndrome. JCI insight 1, e89376
3. Haugen, J., Ulak, M., Chandyo, R. K., Henjum, S., Thorne-Lyman, A. L., Ueland, P. M., Midtun, O., Shrestha, P. S., and Strand, T. A. (2016) Low Prevalence of Vitamin D Insufficiency among Nepalese Infants Despite High Prevalence of Vitamin D Insufficiency among Their Mothers. Nutrients 8
4. Landaas, E. T., Aarsland, T. I., Ulvik, A., Halmoy, A., Ueland, P. M., and Haavik, J. (2016) Vitamin levels in adults with ADHD. BJPsych open 2, 377-384
5. Bjorke-Monsen, A. L., Ulvik, A., Nilsen, R. M., Midttun, O., Roth, C., Magnus, P., Stoltenberg, C., Vollset, S. E., Reichborn-Kjennerud, T., and Ueland, P. M. (2016) Impact of Pre-Pregnancy BMI on B Vitamin and Inflammatory Status in Early Pregnancy: An Observational Cohort Study. Nutrients 8
6. Matejcic, M., de Batlle, J., Ricci, C., Biessy, C., Perrier, F., Huybrechts, I., Weiderpass, E., Boutron-Ruault, M. C., Cadeau, C., His, M., Cox, D. G., Boeing, H., Fortner, R. T., Kaaks, R., Lagiou, P., Trichopoulou, A., Benetou, V., Tumino, R., Panico, S., Sieri, S., Palli, D., Ricceri, F., Bueno-de-Mesquita, H. B. A., Skeie, G., Amiano, P., Sánchez, M. J., Chirlaque, M. D., Barricarte, A., Quirós, J. R., Buckland, G., van Gils, C. H., Peeters, P. H., Key, T. J., Riboli, E., Gylling, B., Zeleniuch-Jacquotte, A., Gunter, M. J., Romieu, I., and Chajès, V. (2017) Biomarkers of folate and vitamin B12 and breast cancer risk: report from the EPIC cohort. Int J Cancer 140, 1246-1259
7. Rotroff, D. M., Joubert, B. R., Marvel, S. W., Haberg, S. E., Wu, M. C., Nilsen, R. M., Ueland, P. M., Nystad, W., London, S. J., and Motsinger-Reif, A. (2016) Maternal smoking impacts key biological pathways in newborns through epigenetic modification in Utero. BMC genomics 17, 976
8. Ding, Y., Pedersen, E. R., Svingen, G. F., Helgeland, O., Gregory, J. F., Loland, K. H., Meyer, K., Tell, G. S., Ueland, P. M., and Nygard, O. K. (2016) Methylenetetrahydrofolate Dehydrogenase 1 Polymorphisms Modify the Associations of Plasma Glycine and Serine With Risk of Acute Myocardial Infarction in Patients With Stable Angina Pectoris in WENBIT (Western Norway B Vitamin Intervention Trial). Circulation. Cardiovascular genetics 9, 541-547
9. Marild, K., Vistnes, M., Tapia, G., Midttun, O., Ueland, P. M., Viken, M. K., Magnus, P., Berg, J. P., Stene, L. C., and Stordal, K. (2017) Midpregnancy and cord blood immunologic biomarkers, HLA genotype, and pediatric celiac disease. The Journal of allergy and clinical immunology 139, 1696-1698
10. Huang, J. Y., Butler, L. M., Midttun, O., Koh, W. P., Ueland, P. M., Wang, R., Jin, A., Gao, Y. T., and Yuan, J. M. (2016) Serum B6 vitamers (pyridoxal 5′-phosphate, pyridoxal, and 4-pyridoxic acid) and pancreatic cancer risk: two nested case-control studies in Asian populations. Cancer causes & control : CCC 27, 1447-1456
11. Fanidi, A., Muller, D. C., Midttun, O., Ueland, P. M., Vollset, S. E., Relton, C., Vineis, P., Weiderpass, E., Skeie, G., Brustad, M., Palli, D., Tumino, R., Grioni, S., Sacerdote, C., Bueno-de-Mesquita, H. B., Peeters, P. H., Boutron-Ruault, M. C., Kvaskoff, M., Cadeau, C., Huerta, J. M., Sanchez, M. J., Agudo, A., Lasheras, C., Quiros, J. R., Chamosa, S., Riboli, E., Travis, R. C., Ward, H., Murphy, N., Khaw, K. T., Trichopoulou, A., Lagiou, P., Papatesta, E. M., Boeing, H., Kuehn, T., Katzke, V., Steffen, A., Johansson, A., Brennan, P., and Johansson, M. (2016) Circulating vitamin D in relation to cancer incidence and survival of the head and neck and oesophagus in the EPIC cohort. Sci Rep 6, 36017
12. Colomina, J. M., Cavalle-Busquets, P., Fernandez-Roig, S., Sole-Navais, P., Fernandez-Ballart, J. D., Ballesteros, M., Ueland, P. M., Meyer, K., and Murphy, M. M. (2016) Maternal Folate Status and the BHMT c.716G>A Polymorphism Affect the Betaine Dimethylglycine Pathway during Pregnancy. Nutrients 8
13. Midttun, O., McCann, A., Aarseth, O., Krokeide, M., Kvalheim, G., Meyer, K., and Ueland, P. M. (2016) Combined Measurement of 6 Fat-Soluble Vitamins and 26 Water-Soluble Functional Vitamin Markers and Amino Acids in 50 muL of Serum or Plasma by High-Throughput Mass Spectrometry. Anal Chem 88, 10427-10436
14. van Lee, L., Tint, M. T., Aris, I. M., Quah, P. L., Fortier, M. V., Lee, Y. S., Yap, F. K., Saw, S. M., Godfrey, K. M., Gluckman, P. D., Chong, Y. S., Kramer, M. S., and Chong, M. F.-F. (2016) Prospective associations of maternal betaine status with offspring weight and body composition at birth: the Growing Up in Singapore Towards healthy Outcomes (GUSTO) cohort study. Am J Clin Nutr 104, 1327-1333
15. Stiksrud, B., Lorvik, K. B., Kvale, D., Mollnes, T. E., Ueland, P. M., Troseid, M., Tasken, K., and Dyrhol-Riise, A. M. (2016) Plasma IP-10 Is Increased in Immunological NonResponders and Associated With Activated Regulatory T Cells and Persisting Low CD4 Counts. Journal of acquired immune deficiency syndromes 73, 138-148
16. Ueland, P. M., McCann, A., Midttun, O., and Ulvik, A. (2017) Inflammation, vitamin B6 and related pathways. Mol Aspects Med 53, 10-27
17. El-Heis, S., Crozier, S. R., Robinson, S. M., Harvey, N. C., Cooper, C., Inskip, H. M., and Godfrey, K. M. (2016) Higher maternal serum concentrations of nicotinamide and related metabolites in late pregnancy are associated with a lower risk of offspring atopic eczema at age 12 months. Clin Exp Allergy 46, 1337-1343
18. Deac, O. M., Mills, J. L., Gardiner, C. M., Shane, B., Quinn, L., Midttun, O., McCann, A., Meyer, K., Ueland, P. M., Fan, R., Lu, Z., Brody, L. C., and Molloy, A. M. (2016) Serum Immune System Biomarkers Neopterin and Interleukin-10 Are Strongly Related to Tryptophan Metabolism in Healthy Young Adults. J Nutr 146, 1801-1806
19. Myte, R., Gylling, B., Schneede, J., Ueland, P. M., Haggstrom, J., Hultdin, J., Hallmans, G., Johansson, I., Palmqvist, R., and Van Guelpen, B. (2016) Components of One-carbon Metabolism Other than Folate and Colorectal Cancer Risk. Epidemiology 27, 787-796
20. Chandyo, R. K., Ulak, M., Sommerfelt, H., Schneede, J., Ueland, P. M., and Strand, T. A. (2016) Nutritional Intake and Status of Cobalamin and Folate among Non-Pregnant Women of Reproductive Age in Bhaktapur, Nepal. Nutrients 8
21. Reese, S. E., Zhao, S., Wu, M. C., Joubert, B. R., Parr, C. L., Haberg, S. E., Ueland, P. M., Nilsen, R. M., Midttun, O., Vollset, S. E., Peddada, S. D., Nystad, W., and London, S. J. (2017) DNA Methylation Score as a Biomarker in Newborns for Sustained Maternal Smoking during Pregnancy. Environmental health perspectives 125, 760-766
22. Magnus, M. C., Karlstad, O., Midtun, O., Haberg, S. E., Tunheim, G., Parr, C. L., Nafstad, P., London, S. J., Nilsen, R. M., Ueland, P. M., and Nystad, W. (2016) Maternal plasma total neopterin and kynurenine/tryptophan levels during pregnancy in relation to asthma development in the offspring. The Journal of allergy and clinical immunology 138, 1319-1325 e1314
23. Ulvik, A., Pedersen, E. R., Svingen, G. F., McCann, A., Midttun, O., Nygard, O., and Ueland, P. M. (2016) Vitamin B-6 catabolism and long-term mortality risk in patients with coronary artery disease. Am J Clin Nutr 103, 1417-1425
24. Molloy, A. M., Pangilinan, F., Mills, J. L., Shane, B., O’Neill, M. B., McGaughey, D. M., Velkova, A., Abaan, H. O., Ueland, P. M., McNulty, H., Ward, M., Strain, J. J., Cunningham, C., Casey, M., Cropp, C. D., Kim, Y., Bailey-Wilson, J. E., Wilson, A. F., and Brody, L. C. (2016) A Common Polymorphism in HIBCH Influences Methylmalonic Acid Concentrations in Blood Independently of Cobalamin. American journal of human genetics 98, 869-882
25. Price, A. J., Travis, R. C., Appleby, P. N., Albanes, D., Barricarte Gurrea, A., Bjorge, T., Bueno-de-Mesquita, H. B., Chen, C., Donovan, J., Gislefoss, R., Goodman, G., Gunter, M., Hamdy, F. C., Johansson, M., King, I. B., Kuhn, T., Mannisto, S., Martin, R. M., Meyer, K., Neal, D. E., Neuhouser, M. L., Nygard, O., Stattin, P., Tell, G. S., Trichopoulou, A., Tumino, R., Ueland, P. M., Ulvik, A., de Vogel, S., Vollset, S. E., Weinstein, S. J., Key, T. J., Allen, N. E., Endogenous Hormones, N. B., and Prostate Cancer Collaborative, G. (2016) Circulating Folate and Vitamin B12 and Risk of Prostate Cancer: A Collaborative Analysis of Individual Participant Data from Six Cohorts Including 6875 Cases and 8104 Controls. European urology 70, 941-951
26. Ulak, M., Chandyo, R. K., Thorne-Lyman, A. L., Henjum, S., Ueland, P. M., Midttun, O., Shrestha, P. S., Fawzi, W. W., Graybill, L., and Strand, T. A. (2016) Vitamin Status among Breastfed Infants in Bhaktapur, Nepal. Nutrients 8, 149
27. Borgeraas, H., Hertel, J. K., Svingen, G. F. T., Pedersen, E. R., Seifert, R., Nygård, O., and Hjelmesæth, J. (2016) Association between Body Mass Index, Asymmetric Dimethylarginine and Risk of Cardiovascular Events and Mortality in Norwegian Patients with Suspected Stable Angina Pectoris. PLoS One 11, e0152029
28. Svingen, G. F., Schartum-Hansen, H., Pedersen, E. R., Ueland, P. M., Tell, G. S., Mellgren, G., Njolstad, P. R., Seifert, R., Strand, E., Karlsson, T., and Nygard, O. (2016) Prospective Associations of Systemic and Urinary Choline Metabolites with Incident Type 2 Diabetes. Clinical chemistry 62, 755-765
29. Borgeraas, H., Hertel, J. K., Seifert, R., Berge, R. K., Bohov, P., Ueland, P. M., Nygard, O., and Hjelmesaeth, J. (2016) Serum trans fatty acids, asymmetric dimethylarginine and risk of acute myocardial infarction and mortality in patients with suspected coronary heart disease: a prospective cohort study. Lipids Health Dis 15, 38
30. Chuang, S. C., Boeing, H., Vollset, S. E., Midttun, O., Ueland, P. M., Bueno-de-Mesquita, B., Lajous, M., Fagherazzi, G., Boutron-Ruault, M. C., Kaaks, R., Kuehn, T., Pischon, T., Drogan, D., Tjonneland, A., Overvad, K., Quiros, J. R., Agudo, A., Molina-Montes, E., Dorronsoro, M., Huerta, J. M., Barricarte, A., Khaw, K. T., Wareham, N. J., Travis, R. C., Trichopoulou, A., Lagiou, P., Trichopoulos, D., Masala, G., Agnoli, C., Tumino, R., Mattiello, A., Peeters, P. H., Weiderpass, E., Palmqvist, R., Ljuslinder, I., Gunter, M., Lu, Y., Cross, A. J., Riboli, E., Vineis, P., and Aleksandrova, K. (2016) Cellular immune activity biomarker neopterin is associated hyperlipidemia: results from a large population-based study. Immunity & ageing : I & A 13, 5
31. Joubert, B. R., den Dekker, H. T., Felix, J. F., Bohlin, J., Ligthart, S., Beckett, E., Tiemeier, H., van Meurs, J. B., Uitterlinden, A. G., Hofman, A., Haberg, S. E., Reese, S. E., Peters, M. J., Andreassen, B. K., Steegers, E. A., Nilsen, R. M., Vollset, S. E., Midttun, O., Ueland, P. M., Franco, O. H., Dehghan, A., de Jongste, J. C., Wu, M. C., Wang, T., Peddada, S. D., Jaddoe, V. W., Nystad, W., Duijts, L., and London, S. J. (2016) Maternal plasma folate impacts differential DNA methylation in an epigenome-wide meta-analysis of newborns. Nature communications 7, 10577
32. Zuo, H., Ueland, P. M., Ulvik, A., Eussen, S. J., Vollset, S. E., Nygard, O., Midttun, O., Theofylaktopoulou, D., Meyer, K., and Tell, G. S. (2016) Plasma Biomarkers of Inflammation, the Kynurenine Pathway, and Risks of All-Cause, Cancer, and Cardiovascular Disease Mortality: The Hordaland Health Study. American journal of epidemiology 183, 249-258
33. Ding, Y. P., Pedersen, E. K., Johansson, S., Gregory, J. F., 3rd, Ueland, P. M., Svingen, G. F., Helgeland, O., Meyer, K., Fredriksen, A., and Nygard, O. K. (2016) B vitamin treatments modify the risk of myocardial infarction associated with a MTHFD1 polymorphism in patients with stable angina pectoris. Nutrition, metabolism, and cardiovascular diseases : NMCD 26, 495-501
34. Vaish, S., White, M., Daly, L., Molloy, A. M., Staines, A., and Sweeney, M. R. (2016) Synthetic folic acid intakes and status in children living in Ireland exposed to voluntary fortification. Am J Clin Nutr 103, 512-518
35. Lysne, V., Strand, E., Svingen, G. F., Bjorndal, B., Pedersen, E. R., Midttun, O., Olsen, T., Ueland, P. M., Berge, R. K., and Nygard, O. (2016) Peroxisome Proliferator-Activated Receptor Activation is Associated with Altered Plasma One-Carbon Metabolites and B-Vitamin Status in Rats. Nutrients 8
36. Degerud, E., Hoff, R., Nygard, O., Strand, E., Nilsen, D. W., Nordrehaug, J. E., Midttun, O., Ueland, P. M., de Vogel, S., and Dierkes, J. (2016) Cosinor modelling of seasonal variation in 25-hydroxyvitamin D concentrations in cardiovascular patients in Norway. Eur J Clin Nutr 70, 517-522
37. Bueno, O., Molloy, A. M., Fernandez-Ballart, J. D., Garcia-Minguillan, C. J., Ceruelo, S., Rios, L., Ueland, P. M., Meyer, K., and Murphy, M. M. (2016) Common Polymorphisms That Affect Folate Transport or Metabolism Modify the Effect of the MTHFR 677C>T Polymorphism on Folate Status. J Nutr 146, 1-8
38. Zwart, S. R., Gregory, J. F., Zeisel, S. H., Gibson, C. R., Mader, T. H., Kinchen, J. M., Ueland, P. M., Ploutz-Snyder, R., Heer, M. A., and Smith, S. M. (2016) Genotype, B-vitamin status, and androgens affect spaceflight-induced ophthalmic changes. FASEB journal : official publication of the Federation of American Societies for Experimental Biology 30, 141-148