6 classes
150μl volume
14 days turn-around time
GC- and LC-MS/MS
65 authentic ISs

3 classes
100μl volume
14 days turn-around time
LC-MS/MS and MALDI MS
17 authentic ISs

4 classes
200μl volume
14 days turn-around time
GC- and LC-MS/MS
x authentic ISs

5 classes
200μl volume
14 days turn-around time
GC- and LC-MS/MS
x authentic ISs

Biomarkers included

Amino acids

Alanine
Arginine
Asparagine
Aspartic acid
Glutamic acid
Glutamine
Glycine
Histidine
Isoleucine
Kynurenine
Leucine
Lysine
Methionine
Ornithine
Phenylalanine
Proline
Sarcosine
Serine
Threonine
Total cysteine
Tryptophan
Tyrosine
Valine

Amino acids and catabolites

2-Aminoadipic acid
2-Hydroxybutyrate
3-Hydroxysiobutyrate
a-Hydroxyglutaric acid
B-Alanine
B-Aminoisobutyrate
B-Hydroxy B-methylbutyric acid
Phenylacetylglutamine

Acylcarnities

BB Butyrobetaine
C0 Carnitine
C2 Acetylcarnitine
C3 Propionylcarnitine
C3-DC Malonylcarnitine
C4 Butyrylcarnitine
C4-OH Hydroxybutyrylcarnitine
C4-DC Succinylcarnitine
iC5 Isovalerylcarnitine
C5-DC Glutarylcarnitine
C5:1 Tiglylcarnitine
C6 Hexanoylcarnitine
C8 Octanoylcarnitine
C10 Decanoylcarnitine
C12 Dodecanoylcarnitine
C14 Tetradecanoylcarnitine
C14-OH Hydroxytetradecanoylcarnitine
C16 Hexadecanoylcarnitine
C16-OH Hydroxyhexadecanoylcarnitine
C18 Octadecanoylcarnitine
C18-OH Hydroxyoctadecanoylcarnitine
C18:1 Octadecenoylcarnitine
C18:2 Octadecadienylcarnitine

TCA metabolites

a-Ketoglutarate
Citrate
Fumarate
Isocitrate
Lactate
Malate
Pyruvate

Ketone bodies

3-Hydroxybutyrate
Acetoacetate

AGEs

Biomarkers included

Kynurenines

Proteins

C-Reactive protein
Calprotectin
Serum Amyloid A

Others

Kynurenine/tryptophan ratio
Neopterin
PAr index (PLP, PL, PA)

Biomarkers included

SCFAs

Acetate
Butyrate
Formate
Isobutyrate
Isovalerate
Propionate
Valerate
α-Methylbutyrate

Indoles

3-Indoxyl sulfate
Imidazole propionate
Indole-3-acetamide
Indole-3-acetate
Indole-3-aldehyde
Indole-3-lactate
Indole-3-propionate

Choline metabolites

Choline
Betaine
DMG
TMAO

Amino acid derived

Phenylacetylglutamine

Biomarkers included

B-vitamins, functional markers, and methyl donors

4-Pyridoxic acid
Betaine
Choline
Cobalamin
Flavin mononucleotide
Folate
Methylmalonic acid
N1-methylnicotinamide
Nicotinamide
Nicotinic acid
Pyridoxal
Pyridoxal 5-phosphate
Pyridoxine
Riboflavin
Thiamine
Thiamine monophosphate
Total homocysteine

Fat-soluble vitamins

25-hydroxy vitamin D2
25-hydroxy vitamin D3
α-Tocopherol (Vit. E)
All-trans retinol (Vit. A)
Phylloquinone (Vit. K1)
y-Tocopherol (Vit. E)

Essential amino acids

Histidine
Isoleucine
Leucine
Lysine
Methionine
Phenylalanine
Threonine
Tryptophan
Valine

Meat and fish intake

1-Methylhistidine
3-Methylhistidine
B-Alanine
Creatine
Creatinine
TMAO

Tobacco use and coffee intake

Cotinine
Trans-3-hydroxycotinine
Trigonelline

Olink Proteomics

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Ready-to-Run

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Mix-and-Match

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