Bevital AS

Biomarkers by platform

This page provides description of most biomarkers, information on indications, optimal sample collection, volume requirements, sample matrix, recommended conditions for transportation and storage, and interpretation of values. ”Reported values” are not strictly ”normal reference range”, which depends on the population, and several factors, including age, gender, ethnicity and procedures for sample handling and analytical technology. ”Reported values” are concentrations that we and others have observed or reported in various cohorts of healthy subjects.

A: GC-MS/MS

TCA metabolites and intermediates. Short-chain fatty acids.

B: GC-MS/MS

Amino and carboxylic acids.

C: LC-MS/MS

Choline derivatives.
Charged, methylated or sulfur amino acids.
Short- and medium-chain acylcarnitines.

D: LC-MS/MS

Kynurenine pathway and B vitamins (B1, B2, B3, B6).

E: LC-MS/MS

Folate species and catabolites.

F: Microbiological assay

Folate (B9) and cobalamin (B12).

G: MALDI-TOF MS

Protein biomarkers and proteoforms.

H: LC-MS/MS

Lipid-soluble vitamins and long-chain acylcarnitines.

I: LC (HILIC)-MS/MS

Short-, medium- and and long-chain acylcarnitines.
May 19, 2022

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