BEVITAL AS

High-Precision Metabolomics

& Proteomics


Decoding Metabolism’s Impact on Health, Disease and Quality of Life
& Proteomics

High-Precision Metabolomics


Decoding Metabolism's Impact on Health, Disease and Quality of Life

From Scientists for Scientists

High-Precision Metabolomics

Bevital´s analytical platforms are designed with authentic isotope-labelled internal standards for each analyte, ensuring the highest precision, reliability and statistical power for targeted metabolomics and validation studies.

Physiological Concentration Ranges

Bevital’s diverse analytical platforms allow quantification at physiologically relevant dynamic ranges from pmol/L to mmol/L in various sample matrices as serum, plasma or CSF. Consequently, Bevital’s metabolomics methods typically result in very few missing data points.

Highly Reliable Quantification

Bevital’s methods ensure highly accurate and reproducible quantification. Our participation in external programs as DEKS, DEQAS, KEQAS, ERNDIM and LABQUALITY are part of our quality control, guaranteeing the highest standards from sample storage to data delivery.

Complete Metabolomic Pathways

Bevital’s pathway panels include dietary biomarkers, metabolic intermediates, vitamins, and derived co-factors, offering a comprehensive view of the targeted metabolomics network, including potential avenues for crosstalk with other pathways.

Full Academic Support

Bevital has been involved in numerous scientific projects and can provide academic support from writing of funding applications, statistical data analysis, to critical review of draft manuscripts.

20+ Years of Experience

Bevital’s staff has extensive experience in developing bio-analytical technologies and applying them in large epidemiological projects. Our workflow ensures optimal sample handling, taking into account pre-analytical stability, matrix effects and minimizing sample consumption.

Metabolomics

Ready-to-Run

Bevital’s analytical repertoire has been thoughtfully and strategically developed, focusing on established biomarkers, specific metabolites, metabolic classes, and key pathways. We offer four pre-designed analytical panels addressing cardiometabolic functions, inflammation and immune activation, gut microbiome health, nutritional and lifestyle markers.

Cardiometabolic

•Acylcarnitines
•AGEs
•Amino acids and catabolites
•Ketone bodies
•TCA metabolites

Inflammation & Immune Activation

•Kynurenines and ratio-derived metabolites
•Neopterin
•Proteins: Calprotectin, CRP, serum amyloid A

Microbiome

•Amino acid derived metabolites
•Choline oxidation
•Indoles
•SCFAs

Nutritional Status & Lifestyle

•B- and fat- soluble vitamins
•Essential amino acids
•Meat & fish intake
•Tobacco use & coffee intake


Cardiometabolic

•Acylcarnitines
•AGEs
•Amino acids and catabolites
•Ketone bodies
•TCA metabolites

Inflammation &
Immune Activation

•Kynurenines and ratio-derived metabolites
•Neopterin
•Proteins: Calprotectin, CRP, SAA



Microbiome

•Amino acid derived metabolites
•Choline oxidation
•Indoles
•SCFAs


Nutritional Status &
Lifestyle

•B- and fat- soluble vitamins
•Essential amino acids
•Meat & fish intake
•Tobacco use & coffee intake


Mix-and-Match

Metabolites, intermediates, vitamins, and co-factors are organized into various categories and can be combined with any individual marker or panel, offering maximum flexibility for your project. Bevital’s methods have been thoroughly validated and published in high-impact journals.

Full flexibility

Not Found What You Are Looking For?

Analytes not listed in our analytical repertoire may be included into existing panels and be analysed by customized assays. Contact our experts to discuss your needs and the strategies to realize your project. Project evaluation should include:

  • Classes and types of compounds
  • Number of samples
  • Sample matrix
  • Time frame
  • Published analytical methods

Multiomics Services

Bevital is a service provider of Olink® and offers 16 different Olink® Target 96&48 panels for high-quality proteomics from 1 µl of sample volume only.

For larger flexibility customers can choose from about 200 proteins and combine them in unique Olink® Flex panels, offering 5 to 30 assays per kit.

Bevital partners with Biogenity, a research organization specializing in omics research and discovery. With Biogenity’s expertise in biostatistics, Bevital provides a seamless workflow from multi-omics project planning to data integration and interpretation. This collaboration enables our customers to expand their projects by incorporating additional omics data, such as transcriptomics and genomics.

Testimonials

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Learn more about our new NAD and Bile Acids panels!

562 entries « 2 of 29 »
21.

Sulistyoningrum, Dian C; Sullivan, Thomas R; Skubisz, Monika; Palmer, Debra J; Wood, Simon; Ueland, Per Magne; McCann, Adrian; Makrides, Maria; Green, Timothy J; Best, Karen P

Maternal serum unmetabolized folic acid concentration following multivitamin and mineral supplementation with or without folic acid after 12 weeks gestation: A randomized controlled trial Journal Article

In: Matern Child Nutr, vol. 20, no. 4, pp. e13668, 2024, ISSN: 1740-8709.

Abstract | Links | BibTeX

22.

Wilson, Edward; Umans, Jacob; Swarovski, Michelle; Minhas, Paras; Midttun, Øivind; Ulvik, Arve Arve; Shahid-Besanti, Marian; Linortner, Patricia; Mhatre, Siddhita; Wang, Qian; Channappa, Divya; Corso, Nicole; Tian, Lu; Fredericks, Carolyn; Kerchner, Geoffrey; Plowey, Edward; Cholerton, Brenna; Ueland, Per; Zabetian, Cyrus; Gray, Nora; Quinn, Joseph; Montine, Thomas; Sha, Sharon; Longo, Frank; Wolk, David; Chen-Plotkin, Alice; Henderson, Victor; Wyss-Coray, Tony; Wagner, Anthony; Mormino, Elizabeth; Aghaeepour, Nima; Poston, Kathleen; Andreasson, Katrin

Parkinson's disease is characterized by vitamin B6-dependent inflammatory kynurenine pathway dysfunction Journal Article

In: Res Sq, 2024, ISSN: 2693-5015.

Abstract | Links | BibTeX

23.

Midtbø, Helga; Ulvik, Arve; Cramariuc, Dana; Meyer, Klaus; Ueland, Per M; Halland, Hilde; Gerdts, Eva

Influence of cardiorespiratory fitness on obesity-associated inflammation in women and men: The FATCOR study Journal Article

In: Nutr Metab Cardiovasc Dis, vol. 34, no. 8, pp. 1942–1949, 2024, ISSN: 1590-3729.

Abstract | Links | BibTeX

24.

Ulak, Manjeswori; Kvestad, Ingrid; Chandyo, Ram K; Schwinger, Catherine; Basnet, Sudha; Shrestha, Merina; Ranjitkar, Suman; Nguyen, Linda Vy; Corona-Pérez, Diana; Vivo, Immaculata De; Ueland, Per M; McCann, Adrian; Strand, Tor A

The Effect of Vitamin B Supplementation on Leukocyte Telomere Length in Mildly Stunted Nepalese Children: A Secondary Outcome of a Randomized Controlled Trial Journal Article

In: J Nutr, vol. 154, no. 8, pp. 2543–2550, 2024, ISSN: 1541-6100.

Abstract | Links | BibTeX

25.

Knapskog, Anne-Brita; Edwin, Trine Holt; Ueland, Per Magne; Ulvik, Arve; Fang, Evandro Fei; Eldholm, Rannveig Sakshaug; Halaas, Nathalie Bodd; Giil, Lasse M; Saltvedt, Ingvild; Watne, Leiv Otto; Aksnes, Mari

Sex-specific associations of kynurenic acid with neopterin in Alzheimer's disease Journal Article

In: Alzheimers Res Ther, vol. 16, no. 1, pp. 167, 2024, ISSN: 1758-9193.

Abstract | Links | BibTeX

26.

Pluvinage, John V; Ngo, Thomas; Fouassier, Camille; McDonagh, Maura; Holmes, Brandon B; Bartley, Christopher M; Kondapavulur, Sravani; Hurabielle, Charlotte; Bodansky, Aaron; Pai, Vincent; Hinman, Sam; Aslanpour, Ava; Alvarenga, Bonny D; Zorn, Kelsey C; Zamecnik, Colin; McCann, Adrian; Asencor, Andoni I; Huynh, Trung; Browne, Weston; Tubati, Asritha; Haney, Michael S; Douglas, Vanja C; Louine, Martineau; Cree, Bruce A C; Hauser, Stephen L; Seeley, William; Baranzini, Sergio E; Wells, James A; Spudich, Serena; Farhadian, Shelli; Ramachandran, Prashanth S; Gillum, Leslie; Hales, Chadwick M; Zikherman, Julie; Anderson, Mark S; Yazdany, Jinoos; Smith, Bryan; Nath, Avindra; Suh, Gina; Flanagan, Eoin P; Green, Ari J; Green, Ralph; Gelfand, Jeffrey M; DeRisi, Joseph L; Pleasure, Samuel J; Wilson, Michael R

Transcobalamin receptor antibodies in autoimmune vitamin B12 central deficiency Journal Article

In: Sci Transl Med, vol. 16, no. 753, pp. eadl3758, 2024, ISSN: 1946-6242.

Abstract | Links | BibTeX

27.

Bråtveit, Marianne; Parys, Anthea Van; Olsen, Thomas; Strand, Elin; Marienborg, Ingvild; Laupsa-Borge, Johnny; Haugsgjerd, Teresa Risan; McCann, Adrian; Dhar, Indu; Ueland, Per Magne; Dierkes, Jutta; Dankel, Simon Nitter; Nygård, Ottar Kjell; Lysne, Vegard

Association between dietary macronutrient composition and plasma one-carbon metabolites and B-vitamin cofactors in patients with stable angina pectoris Journal Article

In: Br J Nutr, vol. 131, no. 10, pp. 1678–1690, 2024, ISSN: 1475-2662.

Abstract | Links | BibTeX

28.

Holthuijsen, Daniëlle D B; van Roekel, Eline H; Bours, Martijn J L; Ueland, Per M; Breukink, Stéphanie O; Janssen-Heijnen, Maryska L G; Keulen, Eric T P; Gigic, Biljana; Gsur, Andrea; Meyer, Klaus; Ose, Jennifer; Ulvik, Arve; Weijenberg, Matty P; Eussen, Simone J P M

Longitudinal associations of plasma kynurenines and ratios with anxiety and depression scores in colorectal cancer survivors up to 12 months post-treatment Journal Article

In: Psychoneuroendocrinology, vol. 163, pp. 106981, 2024, ISSN: 1873-3360.

Abstract | Links | BibTeX

29.

Sandvig, Heidi Vihovde; Aam, Stina; Alme, Katinka N; Lydersen, Stian; Ueland, Per Magne; Ulvik, Arve; Wethal, Torgeir; Saltvedt, Ingvild; Knapskog, Anne-Brita

Neopterin, kynurenine metabolites, and indexes related to vitamin B6 are associated with post-stroke cognitive impairment: The Nor-COAST study Journal Article

In: Brain Behav Immun, vol. 118, pp. 167–177, 2024, ISSN: 1090-2139.

Abstract | Links | BibTeX

30.

Senkin, Sergey; Moody, Sarah; Díaz-Gay, Marcos; Abedi-Ardekani, Behnoush; Cattiaux, Thomas; Ferreiro-Iglesias, Aida; Wang, Jingwei; Fitzgerald, Stephen; Kazachkova, Mariya; Vangara, Raviteja; Le, Anh Phuong; Bergstrom, Erik N; Khandekar, Azhar; Otlu, Burçak; Cheema, Saamin; Latimer, Calli; Thomas, Emily; Atkins, Joshua Ronald; Smith-Byrne, Karl; Penha, Ricardo Cortez Cardoso; Carreira, Christine; Chopard, Priscilia; Gaborieau, Valérie; Keski-Rahkonen, Pekka; Jones, David; Teague, Jon W; Ferlicot, Sophie; Asgari, Mojgan; Sangkhathat, Surasak; Attawettayanon, Worapat; Świątkowska, Beata; Jarmalaite, Sonata; Sabaliauskaite, Rasa; Shibata, Tatsuhiro; Fukagawa, Akihiko; Mates, Dana; Jinga, Viorel; Rascu, Stefan; Mijuskovic, Mirjana; Savic, Slavisa; Milosavljevic, Sasa; Bartlett, John M S; Albert, Monique; Phouthavongsy, Larry; Ashton-Prolla, Patricia; Botton, Mariana R; Neto, Brasil Silva; Bezerra, Stephania Martins; Curado, Maria Paula; de Cássio Zequi, Stênio; Reis, Rui Manuel; Faria, Eliney Ferreira; de Menezes, Nei Soares; Ferrari, Renata Spagnoli; Banks, Rosamonde E; Vasudev, Naveen S; Zaridze, David; Mukeriya, Anush; Shangina, Oxana; Matveev, Vsevolod; Foretova, Lenka; Navratilova, Marie; Holcatova, Ivana; Hornakova, Anna; Janout, Vladimir; Purdue, Mark P; Rothman, Nathaniel; Chanock, Stephen J; Ueland, Per Magne; Johansson, Mattias; McKay, James; Scelo, Ghislaine; Chanudet, Estelle; Humphreys, Laura; de Carvalho, Ana Carolina; Perdomo, Sandra; Alexandrov, Ludmil B; Stratton, Michael R; Brennan, Paul

Geographic variation of mutagenic exposures in kidney cancer genomes Journal Article

In: Nature, vol. 629, no. 8013, pp. 910–918, 2024, ISSN: 1476-4687.

Abstract | Links | BibTeX

31.

Strand, Tor A; McCann, Adrian; Kvestad, Ingrid; Chandyo, Ram K

Vitamin B12 deficiency in pregnant women - Authors' reply Miscellaneous

2024, ISSN: 1474-547X.

Links | BibTeX

32.

Anfinsen, Åslaug Matre; Johannesen, Christina Osland; Myklebust, Vilde Haugen; Rosendahl-Riise, Hanne; McCann, Adrian; Nygård, Ottar Kjell; Dierkes, Jutta; Lysne, Vegard

Time-resolved concentrations of serum amino acids, one-carbon metabolites and B-vitamin biomarkers during the postprandial and fasting state: the Postprandial Metabolism in Healthy Young Adults (PoMet) Study Journal Article

In: Br J Nutr, vol. 131, no. 5, pp. 786–800, 2024, ISSN: 1475-2662.

Abstract | Links | BibTeX

33.

Rim, Sehee; Vedøy, Oda Barth; Brønstad, Ingeborg; McCann, Adrian; Meyer, Klaus; Steinsland, Hans; Hanevik, Kurt

Inflammation, the kynurenines, and mucosal injury during human experimental enterotoxigenic Escherichia coli infection Journal Article

In: Med Microbiol Immunol, vol. 213, no. 1, pp. 2, 2024, ISSN: 1432-1831.

Abstract | Links | BibTeX

34.

Trøseid, Marius; Molinaro, Antonio; Gelpi, Marco; Vestad, Beate; Kofoed, Klaus Fuglsang; Fuchs, Andreas; Køber, Lars; Holm, Kristian; Benfield, Thomas; Ueland, Per M; Hov, Johannes R; Nielsen, Susanne Dam; Knudsen, Andreas Dehlbæk

Gut Microbiota Alterations and Circulating Imidazole Propionate Levels Are Associated With Obstructive Coronary Artery Disease in People With HIV Journal Article

In: J Infect Dis, vol. 229, no. 3, pp. 898–907, 2024, ISSN: 1537-6613.

Abstract | Links | BibTeX

35.

Kok, Dieuwertje E; van Duijnhoven, Fränzel Jb; Lubberman, Floor Je; McKay, Jill A; van Lanen, Anne-Sophie; Winkels, Renate M; Wesselink, Evertine; van Halteren, Henk K; de Wilt, Johannes Hw; Ulrich, Cornelia M; Ulvik, Arve; Ueland, Per M; Kampman, Ellen

Intake and biomarkers of folate and folic acid as determinants of chemotherapy-induced toxicities in patients with colorectal cancer: a cohort study Journal Article

In: Am J Clin Nutr, vol. 119, no. 2, pp. 294–301, 2024, ISSN: 1938-3207.

Abstract | Links | BibTeX

36.

Raju, Sajan C; Molinaro, Antonio; Awoyemi, Ayodeji; Jørgensen, Silje F; Braadland, Peder R; Nendl, Andraz; Seljeflot, Ingebjørg; Ueland, Per M; McCann, Adrian; Aukrust, Pål; Vestad, Beate; Mayerhofer, Cristiane; Broch, Kaspar; Gullestad, Lars; Lappegård, Knut T; Halvorsen, Bente; Kristiansen, Karsten; Hov, Johannes R; Trøseid, Marius

Microbial-derived imidazole propionate links the heart failure-associated microbiome alterations to disease severity Journal Article

In: Genome Med, vol. 16, no. 1, pp. 27, 2024, ISSN: 1756-994X.

Abstract | Links | BibTeX

37.

Braadland, Peder R; Farnes, Ingvild; Kure, Elin H; Yaqub, Sheraz; McCann, Adrian; Ueland, Per M; Labori, Knut Jørgen; Hov, Johannes R

Indole 3-acetate and response to therapy in borderline resectable or locally advanced pancreatic cancer Journal Article

In: Front Oncol, vol. 14, pp. 1488749, 2024, ISSN: 2234-943X.

Abstract | Links | BibTeX

38.

Giil, Lasse Melvaer; Hanseth, Silja; Bojovic, Ognjen; Nordrehaug, Jan Erik; Ueland, Per Magne; Meyer, Klaus; Tell, Grethe S

The inverse association between the apolipoprotein E ε4 allele and C-reactive protein levels is stronger in persons with obesity and diabetes Journal Article

In: Scand J Immunol, vol. 99, no. 1, pp. e13323, 2024, ISSN: 1365-3083.

Abstract | Links | BibTeX

39.

Grymyr, Lisa M D; Mellgren, Gunnar; McCann, Adrian; Gerdts, Eva; Meyer, Klaus; Nadirpour, Saied; Fernø, Johan; Nedrebø, Bjørn G; Cramariuc, Dana

Preoperative risk factors associated with left ventricular dysfunction after bariatric surgery Journal Article

In: Sci Rep, vol. 14, no. 1, pp. 2173, 2024, ISSN: 2045-2322.

Abstract | Links | BibTeX

40.

Kupjetz, Marie; Patt, Nadine; Joisten, Niklas; Ueland, Per Magne; McCann, Adrian; Gonzenbach, Roman; Bansi, Jens; Zimmer, Philipp

Baseline Inflammation but not Exercise Modality Impacts Exercise-induced Kynurenine Pathway Modulation in Persons With Multiple Sclerosis: Secondary Results From a Randomized Controlled Trial Journal Article

In: Int J Tryptophan Res, vol. 17, pp. 11786469241284423, 2024, ISSN: 1178-6469.

Abstract | Links | BibTeX

562 entries « 2 of 29 »

Olink Proteomics

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Customized analyses

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Mix-and-Match

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Ready-to-Run

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